Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | NMT2 | O60551 | 1/20 | 0.34 |
| ▸ | NMT1 | P30419 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27250381 | 0.84 | FOLH1 (0.41) | SIRT6SIRT1FOLH1GNAI3GNAO1 | |
| SCHEMBL20435279 | 0.84 | FOLH1 (0.41) | SIRT6SIRT1FOLH1GNAI3GNAO1 | |
| SCHEMBL18689009 | 0.84 | FOLH1 (0.41) | SIRT6SIRT1FOLH1GNAI3GNAO1 | |
| SCHEMBL12323341 | 0.82 | SIRT6 (0.40) | SIRT6SIRT1FOLH1GNAI3GNAO1 | |
| SCHEMBL20235751 | 0.78 | NMT2 (0.41) | SIRT6SIRT1SLC6A5CPB2NMT2 | |
| SCHEMBL12392036 | 0.78 | FOLH1 (0.35) | SIRT6SIRT1FOLH1GNAI3GNAO1 | |
| SCHEMBL14878853 | 0.77 | SIRT6 (0.42) | SIRT6SIRT1FOLH1GNAI3GNAO1 | |
| SCHEMBL21103612 | 0.77 | GSR (0.53) | GNAI3GNAO1GNAI1GSRCPB2 | |
| SCHEMBL20978516 | 0.77 | SIRT6 (0.42) | SIRT6SIRT1FOLH1GNAI3GNAO1 | |
| SCHEMBL18868852 | 0.77 | GSR (0.53) | GNAI3GNAO1GNAI1GSRCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2301942-A1 | Transition metal complexes with (pyridyl)imidazole ligands and their use | Abbott Diabetes Care Inc. (US) | 2011-03-30 | — | — | EP | disclosed |