SCHEMBL27250381

SCHEMBL27250381

CN[C@H](CCCCN)C(=O)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 1/20 0.41
▸ GSR P00390 1/20 0.39
▸ SIRT6 Q8N6T7 1/20 0.39
▸ SIRT1 Q96EB6 1/20 0.39
▸ RNPEP Q9H4A4 1/20 0.38
▸ NMT2 O60551 1/20 0.36
▸ NMT1 P30419 1/20 0.36
▸ GNAI3 P08754 1/20 0.36
▸ GNAO1 P09471 1/20 0.36
▸ GNAI1 P63096 1/20 0.36
▸ SLC6A5 Q9Y345 1/20 0.35
▸ CPB2 Q96IY4 6/20 0.35
▸ PAOX Q6QHF9 2/20 0.34
▸ MMP2 P08253 1/20 0.34
▸ MMP9 P14780 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20435279 1.00 FOLH1 (0.41) FOLH1GSRSIRT6SIRT1RNPEP
SCHEMBL18689009 1.00 FOLH1 (0.41) FOLH1GSRSIRT6SIRT1RNPEP
SCHEMBL12392036 0.94 FOLH1 (0.35) FOLH1GSRSIRT6SIRT1RNPEP
SCHEMBL22536882 0.86 GABRR1 (0.41) —
SCHEMBL12812737 0.84 SIRT6 (0.39) FOLH1GSRSIRT6SIRT1RNPEP
SCHEMBL13573523 0.83 FOLH1 (0.40) FOLH1GSRSIRT6SIRT1RNPEP
SCHEMBL27250343 0.83 FOLH1 (0.40) FOLH1GSRSIRT6SIRT1RNPEP
SCHEMBL7604714 0.83 FOLH1 (0.40) FOLH1GSRSIRT6SIRT1RNPEP
SCHEMBL22062262 0.82 CA1 (0.44) —
SCHEMBL14961163 0.81 SIRT6 (0.43) FOLH1GSRSIRT6SIRT1RNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209382-A1 NANOPARTICLES AND BIOTEMPLATES WITH TUNABLE LENGTH AND METHODS OF MANUFACTURING THE SAME UNIVERSITY OF DELAWARE 2024-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240209382-A1 NANOPARTICLES AND BIOTEMPLATES WITH TUNABLE LENGTH AND METHODS OF MANUFACTURING THE SAME RNGTT, HBS1L, BROX FOLH1 1684/4885GSR 2461/4885SIRT6 3742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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