Phosphine

Phosphine

SCHEMBL1868906

CCCCOS(=O)(=O)C(F)(F)C(F)C(F)(F)F.P

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 10/20 0.41
CA2 P00918 10/20 0.41
CA9 Q16790 8/20 0.36
CA12 O43570 3/20 0.35
CA7 P43166 3/20 0.35
CA14 Q9ULX7 3/20 0.35
CA3 P07451 2/20 0.35
CA4 P22748 2/20 0.35
CA6 P23280 2/20 0.35
CA5A P35218 2/20 0.35
CA5B Q9Y2D0 2/20 0.35
RECQL P46063 2/20 0.34
GLA P06280 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
MAPK1 P28482 1/20 0.34
EPHX2 P34913 1/20 0.34
BLM P54132 1/20 0.34
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4369370 0.84 CA2 (0.45) CA1CA2CA9CA12CA7
SCHEMBL4802763 0.76 CA2 (0.44) CA1CA2CA9CA12CA7
SCHEMBL777643 0.75 CA2 (0.52) CA1CA2CA9CA12CA7
Fluoride SCHEMBL27893472 0.74 CA1 (0.50) CA1CA2CA9CA12CA7
SCHEMBL29170929 0.74 CA1 (0.50) CA1CA2CA9CA12CA7
SCHEMBL27930318 0.74 CA1 (0.50) CA1CA2CA9CA12CA7
SCHEMBL27912318 0.74 CA1 (0.50) CA1CA2CA9CA12CA7
SCHEMBL1858855 0.73 LMNA (0.32) HPGD
SCHEMBL575505 0.71 CA1 (0.32) CA1CA2CA9CA12CA7
SCHEMBL576159 0.71 CA1 (0.37) CA1CA2CA9CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2118194-B1 FLAME RETARDANT POLYCARBONATE COMPOSITIONS DU PONT (US) 2014-12-03 EP disclosed
US-20110195212-A1 Flame Retardant Polycarbonate Compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-08-11 US disclosed
US-7947770-B2 blend of polycarbonate resin prepared from diphenylcarbonate and 2,2-bis(4-hydroxyphenyl)propane; polytetrafluoroethylene antidrip agent; tetrafluoroalkylsulfonate or hexafluorodialkylsulfonimide salt of Na, K, Cs, Li or a pyridium, pydridazinium, phosphonium, ammonium etc.; protective devices E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-05-24 US disclosed
US-20080221241-A1 Flame Retardant Polycarbonate Compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-09-11 US disclosed