SCHEMBL4369370

SCHEMBL4369370

CCCCOS(=O)(=O)C(F)(F)C(F)F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 13/20 0.45
CA1 P00915 11/20 0.45
CA9 Q16790 8/20 0.39
CA12 O43570 3/20 0.38
CA7 P43166 3/20 0.38
CA14 Q9ULX7 3/20 0.38
CA3 P07451 2/20 0.38
CA4 P22748 2/20 0.38
CA6 P23280 2/20 0.38
CA5A P35218 2/20 0.38
CA5B Q9Y2D0 2/20 0.38
RECQL P46063 2/20 0.37
TSHR P16473 2/20 0.37
GLA P06280 1/20 0.37
HPGD P15428 1/20 0.37
MAPK1 P28482 1/20 0.37
EPHX2 P34913 1/20 0.37
BLM P54132 1/20 0.37
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL576159 0.88 CA1 (0.37) CA2CA1CA9CA12CA7
SCHEMBL575505 0.88 CA1 (0.32) CA2CA1CA9CA12CA7
Phosphine SCHEMBL1868906 0.84 CA1 (0.41) CA2CA1CA9CA12CA7
SCHEMBL4802763 0.80 CA2 (0.44) CA2CA1CA9CA12CA7
SCHEMBL777643 0.79 CA2 (0.52) CA2CA1CA9CA12CA7
SCHEMBL29170929 0.78 CA1 (0.50) CA2CA1CA9CA12CA7
Fluoride SCHEMBL27893472 0.78 CA1 (0.50) CA2CA1CA9CA12CA7
SCHEMBL27930318 0.78 CA1 (0.50) CA2CA1CA9CA12CA7
SCHEMBL27912318 0.78 CA1 (0.50) CA2CA1CA9CA12CA7
SCHEMBL357236 0.76 CHRM5 (0.31) TSHRBLMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009073427-A1 FLUORINATED ALKANESULFONIC ACID ESTERS AND AMIDES AND PROCESSES FOR MAKING AND USING THE SAME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-11 WO disclosed
WO-2009073426-A2 FLUORINATED ALKANESULFONIC ACID ANHYDRIDES AND PROCESSES FOR MAKING THE SAME E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-06-11 WO disclosed
US-20090137831-A1 Fluorinated Alkanesulfonic Acid Esters and Amides and Processes for Making and Using the Same E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-28 US disclosed
US-20090137840-A1 Fluorinated Alkanesulfonic Acid Anhydrides and Processes for Making the Same E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-28 US disclosed