Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2680684 | 0.82 | MAPT (0.41) | ALDH1A1SMN1; SMN2TDP1HPGDMAPT | |
| SCHEMBL11145825 | 0.80 | PARP10 (0.42) | ALDH1A1SMN1; SMN2TSHRCA1CA2 | |
| SCHEMBL4774336 | 0.80 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2SRD5A2TDP1HPGD | |
| SCHEMBL3278080 | 0.77 | PGR (0.34) | ALDH1A1SMN1; SMN2CA2KDM4EMEN1 | |
| SCHEMBL578580 | 0.76 | TSHR (0.52) | ALDH1A1SMN1; SMN2TSHRTP53SRD5A2 | |
| SCHEMBL2780243 | 0.74 | TSHR (0.50) | ALDH1A1SMN1; SMN2TSHRTP53SRD5A2 | |
| SCHEMBL6631569 | 0.73 | TSHR (0.48) | ALDH1A1SMN1; SMN2TSHRTP53SRD5A2 | |
| SCHEMBL185207 | 0.73 | TSHR (0.48) | ALDH1A1SMN1; SMN2TSHRTP53SRD5A2 | |
| SCHEMBL4957915 | 0.73 | TSHR (0.48) | ALDH1A1SMN1; SMN2TSHRTP53SRD5A2 | |
| SCHEMBL9901799 | 0.72 | CA12 (0.42) | ALDH1A1CA12CA9HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1262676-A | Pyridine derivatives | NOVARTIS AG (CH) | 2000-08-09 | — | — | CN | claimed |
| EP-0998459-A2 | PYRIDINE DERIVATIVES | Novartis AG (CH) | 2000-05-10 | — | — | EP | claimed |
| WO-1999002497-A2 | PYRIDINE DERIVATIVES | NOVARTIS AG (CH) | 1999-01-21 | — | — | WO | claimed |
| US-5281263-A | Disazo dyes for inks printed paper | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-25 | — | — | US | claimed |
| US-20210094907-A1 | SMALL MOLECULES FOR DISRUPTING THE SUPER ELONGATION COMPLEX AND INHIBITING TRANSCRIPTION ELONGATION FOR CANCER THERAPY | NORTHWESTERN UNIVERSITY | 2021-04-01 | — | — | US | disclosed |
| WO-2019183373-A1 | SMALL MOLECULES FOR DISRUPTING THE SUPER ELONGATION COMPLEX AND INHIBITING TRANSCRIPTION ELONGATION FOR CANCER THERAPY | NORTHWESTERN UNIVERSITY (US) | 2019-09-26 | — | — | WO | disclosed |
| EP-2824101-B1 | NOVEL COMPOUND, AND SUPPORT MATERIAL HAVING SAID NOVEL COMPOUND SUPPORTED THEREON | ADEKA CORP (JP) | 2018-05-09 | — | — | EP | disclosed |
| US-9496095-B2 | Compound and carrier system having the compound | ADEKA CORPORATION (JP) | 2016-11-15 | — | — | US | disclosed |
| CN-105131152-A | Marine organism polysaccharide copper compound, preparation thereof and application of marine organic polysaccharide copper compound serving as agricultural bactericide | INST OCEANOLOGY CHINESE ACAD | 2015-12-09 | — | — | CN | disclosed |
| EP-2824101-A1 | NOVEL COMPOUND, AND SUPPORT MATERIAL HAVING SAID NOVEL COMPOUND SUPPORTED THEREON | Adeka Corporation (JP) | 2015-01-14 | — | — | EP | disclosed |
| US-20140353553-A1 | NOVEL COMPOUND AND CARRIER SYSTEM HAVING THE COMPOUND | ADEKA CORPORATION (JP) | 2014-12-04 | — | — | US | disclosed |
| US-8741932-B2 | Imidazopyridine derivatives | Piramal Enterprises Limited (IN) | 2014-06-03 | — | — | US | disclosed |
| US-5281263-A | Disazo dyes for inks printed paper | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-25 | — | — | US | disclosed |
| US-5279656-A | Containing sulpho or carboxy group | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-18 | — | — | US | disclosed |
| EP-0572419-A1 | ANIONIC DISAZO DYES. | ZENECA LTD (GB) | 1993-12-08 | — | — | EP | disclosed |
| EP-0559310-A1 | Ink compositions | ZENECA LIMITED (GB) | 1993-09-08 | — | — | EP | disclosed |
| EP-0542420-A1 | Anionic xanthene derivatives and their use in inks | ZENECA LIMITED (GB) | 1993-05-19 | — | — | EP | disclosed |
| US-5189154-A | Ink jet printing dyes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-23 | — | — | US | disclosed |
| WO-1992013037-A1 | ANIONIC DISAZO DYES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-08-06 | — | — | WO | disclosed |
| EP-0468649-A1 | Anionic compounds | ZENECA LIMITED (GB) | 1992-01-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094907-A1 | SMALL MOLECULES FOR DISRUPTING THE SUPER ELONGATION COMPLEX AND INHIBITING TRANSCRIPTION ELONGATION FOR CANCER THERAPY | SUB1, ELL, MED16 | ALDH1A1 4571/4885SMN1; SMN2 1517/4885TSHR 3478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.