Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954042 | 0.79 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2DPP4MAPT | |
| SCHEMBL6919191 | 0.78 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2DPP4POLBMAPT | |
| SCHEMBL2446348 | 0.78 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2DPP4POLBMAPT | |
| SCHEMBL11605479 | 0.76 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2DPP4POLBMAPT | |
| Dichlormid SCHEMBL20564640 | 0.76 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2DPP4POLBMAPT | |
| Dichlormid SCHEMBL117463 | 0.76 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2DPP4POLBMAPT | |
| SCHEMBL2187457 | 0.74 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2DPP4POLBMAPT | |
| SCHEMBL11668092 | 0.72 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2DPP4POLBMAPT | |
| SCHEMBL11413701 | 0.71 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2DPP4 | |
| SCHEMBL2446346 | 0.71 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2DPP4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114855-B1 | METHOD FOR PRODUCING DIHALO ACETOACETIC ALKYL ESTERS | BAYER IP GMBH (DE) | 2016-07-27 | — | — | EP | disclosed |
| US-8044231-B2 | Method for producing dihalo acetoacetic alkyl esters | BAYER CROPSCIENCE AG (DE) | 2011-10-25 | — | — | US | disclosed |
| US-7939673-B2 | Process for preparing 3-dihalomethyl-pyrazole-4-carboxylic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2011-05-10 | — | — | US | disclosed |
| EP-2057126-B1 | PROCESS FOR PREPARING 3-DIHALOMETHYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-11-10 | — | — | EP | disclosed |
| US-20100121095-A1 | METHOD FOR PRODUCING DIHALO ACETOACETIC ALKYL ESTERS | BAYER CROPSCIENCE AG (DE) | 2010-05-13 | — | — | US | disclosed |
| US-20090326242-A1 | PROCESS FOR PREPARING 3-DIHALOMETHYL-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-12-31 | — | — | US | disclosed |
| EP-2114855-A2 | METHOD FOR PRODUCING DIHALO ACETOACETIC ALKYL ESTERS | Bayer CropScience Aktiengesellschaft (DE) | 2009-11-11 | — | — | EP | disclosed |
| EP-2057126-A2 | PROCESS FOR PREPARING 3-DIHALOMETHYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008092583-A2 | METHOD FOR PRODUCING DIHALO ACETOACETIC ALKYL ESTERS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-08-07 | — | — | WO | disclosed |
| WO-2008022777-A2 | PROCESS FOR PREPARING 3-DIHALOMETHYLPYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326242-A1 | PROCESS FOR PREPARING 3-DIHALOMETHYL-PYRAZOLE-4-CARBOXYLIC ACID DERIVATIVES | HRH4, SUV39H2, SUV39H1 | ALDH1A1 87/4885SMN1; SMN2 4613/4885DPP4 1303/4885 |
| US-20100121095-A1 | METHOD FOR PRODUCING DIHALO ACETOACETIC ALKYL ESTERS | DAO, ACADM, APEH | ALDH1A1 76/4885SMN1; SMN2 4502/4885DPP4 1508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.