SCHEMBL2187457

SCHEMBL2187457

C=CCN(CC=C)C(=O)C(C)O

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
DPP4 P27487 2/20 0.41
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
TSHR P16473 1/20 0.33
MAPT P10636 1/20 0.33
TP53 P04637 1/20 0.32
POLB P06746 1/20 0.32
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 1/20 0.31
NPSR1 Q6W5P4 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7771316 0.82 ZDHHC20 (0.42) ALDH1A1DPP4KMT2AMEN1
SCHEMBL6919191 0.81 ALDH1A1 (0.48) ALDH1A1DPP4KMT2AMEN1SMN1; SMN2
SCHEMBL2446348 0.81 ALDH1A1 (0.48) ALDH1A1DPP4KMT2AMEN1SMN1; SMN2
SCHEMBL2185036 0.81 ALDH1A1 (0.37) ALDH1A1DPP4KMT2AMEN1
SCHEMBL28876474 0.80 ALDH1A1 (0.34) ALDH1A1DPP4KMT2AMEN1TSHR
SCHEMBL13137730 0.78 ALDH1A1 (0.42) ALDH1A1DPP4KMT2AMEN1SMN1; SMN2
SCHEMBL11605479 0.74 ALDH1A1 (0.46) ALDH1A1DPP4SMN1; SMN2MAPTPOLB
SCHEMBL1869152 0.74 ALDH1A1 (0.46) ALDH1A1DPP4SMN1; SMN2MAPTPOLB
Dichlormid SCHEMBL20564640 0.74 ALDH1A1 (0.46) ALDH1A1DPP4KMT2AMEN1SMN1; SMN2
Dichlormid SCHEMBL117463 0.74 ALDH1A1 (0.46) ALDH1A1DPP4KMT2AMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3259050-B1 CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS MERCK MILLIPORE LTD (IE) 2020-06-10 EP claimed
US-10144702-B2 Method for the manufacture of N,N-dialkyllactamide PURAC BIOCHEM B.V. (NL) 2018-12-04 US claimed
US-9962691-B2 Chromatography membranes formed by thiol-ene or thiol-yne click polymerization reactions NATRIX SEPARATIONS INC. (CA) 2018-05-08 US claimed
EP-3259050-A1 CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS Natrix Separations Inc. (CA) 2017-12-27 EP claimed
US-20170298009-A1 METHOD FOR THE MANUFACTURE OF N,N-DIALLKYLLACTAMIDE PURAC BIOCHEM BV (NL) 2017-10-19 US claimed
WO-2016132224-A1 CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS NATRIX SEPARATIONS INC. (CA) 2016-08-25 WO claimed
US-20160243538-A1 Chromatography Membranes Formed by Thiol-Ene or Thiol-Yne Click Polymerization Reactions MERCK MILLIPORE LTD. (IE) 2016-08-25 US claimed
EP-2346812-B1 PROCESS FOR MANUFACTURING N,N-DIALKYL LACTAMIDE PURAC BIOCHEM BV (NL) 2013-04-24 EP claimed
WO-2024133435-A1 LIQUID RHEOLOGY CONTROL AGENT BYK-CHEMIE GMBH (DE) 2024-06-27 WO disclosed
US-11383229-B2 Methods of separating substances from fluids MERCK MILLIPORE LTD. (IE) 2022-07-12 US disclosed
US-20210060541-A1 METHODS OF SEPARATING SUBSTANCES FROM FLUIDS MERCK MILLIPORE LTD. (IE) 2021-03-04 US disclosed
EP-3778001-A1 CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS Merck Millipore Ltd. (IE) 2021-02-17 EP disclosed
US-10864510-B2 Methods of separating substances from fluids MERCK MILLIPORE LTD. (IE) 2020-12-15 US disclosed
EP-3259050-B1 CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS MERCK MILLIPORE LTD (IE) 2020-06-10 EP disclosed
WO-2016132224-A1 CHROMATOGRAPHY MEMBRANES FORMED BY THIOL-ENE OR THIOL-YNE CLICK POLYMERIZATION REACTIONS NATRIX SEPARATIONS INC. (CA) 2016-08-25 WO disclosed
WO-2016050894-A1 METHOD FOR THE MANUFACTURE OF N, N-DIALLKYLLACTAMIDE PURAC BIOCHEM BV (NL) 2016-04-07 WO disclosed
CN-102209706-B Process for producing N, N-dialkyl lactamide PURAC BIOCHEM BV 2014-07-23 CN disclosed
CN-102209706-A Process for producing N, N-dialkyl lactamide JAN KRIEKEN VAN 2011-10-05 CN disclosed
EP-2346812-A1 PROCESS FOR MANUFACTURING N,N-DIALKYL LACTAMIDE PURAC Biochem BV (NL) 2011-07-27 EP disclosed
WO-2010037776-A1 PROCESS FOR MANUFACTURING N,N-DIALKYL LACTAMIDE PURAC BIOCHEM BV (NL) 2010-04-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160243538-A1 Chromatography Membranes Formed by Thiol-Ene or Thiol-Yne Click Polymerization Reactions TST, TXN, GNE ALDH1A1 1719/4885DPP4 4619/4885KMT2A 4177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.