SCHEMBL2446346

SCHEMBL2446346

C=CCN(CC=C)C(=O)C(O)C(O)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
TSHR P16473 2/20 0.42
DPP4 P27487 2/20 0.36
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 2/20 0.31
HPGD P15428 1/20 0.30
ALOX12 P18054 1/20 0.30
CCR6 P51684 1/20 0.30
CYP2C9 P11712 1/20 0.30
PDE4A P27815 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2446348 0.91 ALDH1A1 (0.48) ALDH1A1DPP4POLBSMN1; SMN2LMNA
SCHEMBL6919191 0.91 ALDH1A1 (0.48) ALDH1A1DPP4POLBSMN1; SMN2LMNA
SCHEMBL612188 0.82 ALDH1A1 (0.41) ALDH1A1DPP4POLBSMN1; SMN2
SCHEMBL14521230 0.82 ALDH1A1 (0.41) ALDH1A1DPP4POLBSMN1; SMN2
SCHEMBL4342168 0.79 ALDH1A1 (0.38) ALDH1A1DPP4POLBSMN1; SMN2
Acrylamide SCHEMBL7521468 0.77 ALDH1A1 (0.39) ALDH1A1TSHRDPP4POLB
SCHEMBL16191438 0.77 ALDH1A1 (0.37) ALDH1A1DPP4POLBSMN1; SMN2
Cadaverine Tartrate SCHEMBL5831142 0.77 TSHR (0.43) ALDH1A1TSHRLMNACYP2C9PDE4A
SCHEMBL12610741 0.75 ALDH1A1 (0.38) ALDH1A1DPP4POLBSMN1; SMN2
SCHEMBL2187457 0.74 ALDH1A1 (0.45) ALDH1A1TSHRDPP4POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115245590-A Novel degradable embolism microsphere and preparation method thereof 苏州浩微生物医疗科技有限公司 2022-10-28 CN claimed
CN-115245589-B Novel degradable embolism microsphere with controllable particle size and preparation method thereof 苏州浩微生物医疗科技有限公司 2024-08-20 CN disclosed
CN-115245589-A Novel degradable embolism microsphere with controllable particle size and preparation method thereof 苏州浩微生物医疗科技有限公司 2022-10-28 CN disclosed
CN-115245590-A Novel degradable embolism microsphere and preparation method thereof 苏州浩微生物医疗科技有限公司 2022-10-28 CN disclosed
EP-2367618-A1 MICROSPHERES Akzo Nobel N.V. (NL) 2011-09-28 EP disclosed
WO-2010072663-A1 MICROSPHERES AKZO NOBEL N.V. (NL) 2010-07-01 WO disclosed