SCHEMBL18691968

SCHEMBL18691968

CC(C)(C)[Si](C)(C)OC(=O)C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1899461 0.79 TSHR (0.34)
SCHEMBL2144171 0.76 NFE2L2 (0.54)
SCHEMBL2144162 0.76 NFE2L2 (0.54)
SCHEMBL15272637 0.74
SCHEMBL1061431 0.74
SCHEMBL28706826 0.74
SCHEMBL22664769 0.73 TDP1 (0.39)
SCHEMBL475925 0.72 ALDH1A1 (0.33)
SCHEMBL22558041 0.72 ALDH1A1 (0.32)
SCHEMBL4578623 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111989080-B Dental impression material 登特斯普伊德特雷有限公司 2023-03-14 CN claimed
CN-108135782-B Dental composition 登特斯普伊德特雷有限公司 2022-03-22 CN claimed
CN-111989080-A Dental impression material 登特斯普伊德特雷有限公司 2020-11-24 CN claimed
CN-113164328-B Difunctional and multifunctional coinitiators in dental compositions 登士柏德特里有限公司 2024-02-27 CN disclosed
CN-112135598-B Macromer-based photocurable dental impression material 登士柏希罗纳有限公司 2023-12-22 CN disclosed
CN-111225648-B Photocurable dental compositions 登特斯普伊德特雷有限公司 2023-03-31 CN disclosed
CN-111989080-B Dental impression material 登特斯普伊德特雷有限公司 2023-03-14 CN disclosed
CN-112166159-B Photocurable dental impression material based on macromonomers 登士柏希罗纳有限公司 2022-10-21 CN disclosed
CN-108697587-B Dental composition 登特斯普伊德特雷有限公司 2022-06-17 CN disclosed
CN-108135782-B Dental composition 登特斯普伊德特雷有限公司 2022-03-22 CN disclosed
CN-110023320-B Dental composition 登特斯普伊德特雷有限公司 2022-02-18 CN disclosed
CN-111225648-A Photocurable dental compositions 登特斯普伊德特雷有限公司 2020-06-02 CN disclosed
US-10588830-B2 Dental composition DENTSPLY SIRONA INC. (US) 2020-03-17 US disclosed
EP-3359118-B1 DENTAL COMPOSITION DENTSPLY DETREY GMBH (DE) 2020-01-29 EP disclosed
US-20190117522-A1 DENTAL COMPOSITION DENTSPLY SIRONA INC. (US) 2019-04-25 US disclosed
US-20180303722-A1 DENTAL COMPOSITION DENTSPLY SIRONA INC. (US) 2018-10-25 US disclosed
WO-2017178383-A1 DENTAL COMPOSITION DENTSPLY DETREY GMBH (DE) 2017-10-19 WO disclosed
EP-3231413-A1 DENTAL COMPOSITION DENTSPLY DETREY GmbH (DE) 2017-10-18 EP disclosed
WO-2017060459-A1 DENTAL COMPOSITION DENTSPLY DETREY GMBH (DE) 2017-04-13 WO disclosed
EP-3153150-A1 DENTAL COMPOSITION Dentsply DeTrey GmbH (DE) 2017-04-12 EP disclosed