SCHEMBL1869231

SCHEMBL1869231

C=CC(=O)NC(CCC)NC(=O)C=C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.52
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
TAS1R3 Q7RTX0 2/20 0.40
TAS1R1 Q7RTX1 2/20 0.40
ALDH1A1 P00352 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
MAPK1 P28482 1/20 0.39
HDAC7 Q8WUI4 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
CYP2C19 P33261 1/20 0.35
ACACB O00763 2/20 0.35
CHRM1 P11229 1/20 0.34
AKR1A1 P14550 1/20 0.34
CHRM3 P20309 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4026662 0.88 ZDHHC20 (0.48) TSHRZDHHC20ZDHHC2ALDH1A1TDP1
SCHEMBL16229094 0.87 TSHR (0.53) TSHRZDHHC20ZDHHC2TAS1R3TAS1R1
SCHEMBL27612238 0.86 ZDHHC20 (0.52) TSHRZDHHC20ZDHHC2ALDH1A1MAPK1
SCHEMBL20788036 0.84 ZDHHC20 (0.55) TSHRZDHHC20ZDHHC2MAPK1PLA2G2C
SCHEMBL28051928 0.83 TAS1R3 (0.58) TSHRZDHHC20ZDHHC2TAS1R3TAS1R1
SCHEMBL108348 0.82 TSHR (0.56) TSHRZDHHC20ZDHHC2TAS1R3TAS1R1
SCHEMBL10686469 0.82 TSHR (0.50) TSHRZDHHC20ZDHHC2ALDH1A1TDP1
SCHEMBL325416 0.81 TSHR (0.56) TSHRZDHHC20ZDHHC2TAS1R3TAS1R1
SCHEMBL399092 0.81 TSHR (0.50) TSHRZDHHC20ZDHHC2TAS1R3TAS1R1
SCHEMBL8976929 0.79 TSHR (0.48) TSHRZDHHC20ZDHHC2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11597789-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2023-03-07 US claimed
US-11092574-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2021-08-17 US claimed
US-20200239680-A1 INTERPENETRATING POLYMER NETWORK CONTAINING CROSS-LINKED POLY(N-VINYLAMINE) KEMIRA OYJ (FI) 2020-07-30 US claimed
US-20190056360-A1 MATERIALS FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY AND PROCESSES FOR PREPARATION AND USE THEREOF FOR ANALYSIS OF GLYCOPROTEINS AND GLYCOPEPTIDES WATERS TECHNOLOGIES CORPORATION 2019-02-21 US claimed
US-10189935-B2 Water soluble cross-linked block copolymers KEMIRA OYJ (FI) 2019-01-29 US claimed
US-10174134-B2 Polymer product, method for producing the polymer and use of the polymer KEMIRA OYJ (FI) 2019-01-08 US claimed
US-10119944-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2018-11-06 US claimed
EP-3204436-B1 POLYMER PRODUCT, METHOD FOR PRODUCING THE POLYMER AND USE OF THE POLYMER KEMIRA OYJ (FI) 2018-08-01 EP claimed
CN-108348402-A Polymerizable composition based on thermally cleavable compounds 义获嘉伟瓦登特公司 2018-07-31 CN claimed
US-20180194906-A1 A method for producing a material with a network of at least two polymers, a product thereof and use of the product KEMIRA OYJ (FI) 2018-07-12 US claimed
EP-1282732-B1 FLUORESCENT MONOMERS AND TAGGED TREATMENT POLYMERS CONTAINING SAME FOR USE IN INDUSTRIAL WATER SYSTEMS ONDEO NALCO CO (US) 2009-09-30 EP claimed
CN-1968970-A Inclusion complexes of unsaturated monomers, their polymers and process for preparation thereof COUNCIL SCIENT IND RES (IN) 2007-05-23 CN claimed
EP-1786054-A1 ELECTROLYTE MEMBRANE AND FUEL CELL UTILIZING THE ELECTROLYTE MEMBRANE TOAGOSEI CO., LTD. (JP) 2007-05-16 EP claimed
EP-0769306-B1 Multi-coating stainless steel guidewire TARGET THERAPEUTICS INC (US) 2003-05-28 EP claimed
EP-0606742-B1 Bile acid sequestrant ROHM & HAAS (US) 1997-11-19 EP claimed
EP-0403395-B1 Process for the one-step preparation of cross-linked poly beta-alanine from acrylamide and a polyfunctional compound copolymerisable therewith OREAL (FR) 1996-04-03 EP claimed
US-5451397-A Crosslinked amino functional acrylic amide polymer, reducing blood cholesterol levels ROHM AND HAAS COMPANY (US) 1995-09-19 US claimed
EP-0606742-A1 Bile acid sequestrant ROHM AND HAAS COMPANY (US) 1994-07-20 EP claimed
US-5077058-A One step process for preparing cross-linked poly-β-alanine microspheres from acrylamide and a copolymerisable polyfunctional compound L'OREAL (FR) 1991-12-31 US claimed
EP-0403395-A1 Process for the one-step preparation of cross-linked poly beta-alanine from acrylamide and a polyfunctional compound copolymerisable therewith L'OREAL (FR) 1990-12-19 EP claimed