SCHEMBL18696159

SCHEMBL18696159

COc1cc(CO)c2cc(C(C)C)c3c(c2c1)OC(c1ccccc1)(c1ccc(N(C)C)cc1)C=C3

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
KDM1A O60341 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2612375 0.90
SCHEMBL12259683 0.87 MEN1 (0.34) MEN1KMT2AKDM1A
SCHEMBL7568969 0.84 PTPN1 (0.34) MEN1KMT2AKDM1A
SCHEMBL6480424 0.78 SLC2A1 (0.32) MEN1KMT2A
SCHEMBL12347484 0.77 EIF4A1 (0.35) MEN1KMT2A
SCHEMBL7525851 0.76 TDP1 (0.32) MEN1KMT2AKDM1A
SCHEMBL10102271 0.75 MEN1 (0.34) MEN1KMT2A
SCHEMBL7569354 0.75 TDP1 (0.35) MEN1KMT2A
SCHEMBL12952370 0.75 TDP1 (0.33) MEN1KMT2A
SCHEMBL13898436 0.75 EIF4A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE46357-E1 Photochromic film, photochromic lens comprising the same, and method of manufacturing photochromic lens HOYA CORPORATION (JP) 2017-04-04 US disclosed