Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.65 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.65 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | HMGCR | P04035 | 2/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8846271 | 0.88 | RXRA (0.64) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL244423 | 0.88 | RXRA (0.67) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL29419163 | 0.88 | RXRA (0.67) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL28287583 | 0.88 | RXRA (0.64) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL526489 | 0.86 | RXRA (0.68) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL10129907 | 0.86 | RXRA (0.68) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL526488 | 0.86 | RXRA (0.68) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL18947956 | 0.86 | RXRA (0.64) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL29466456 | 0.84 | RXRA (0.75) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL1844436 | 0.84 | RXRA (0.75) | RXRAPRKAA2NR1I2NR4A2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210008217-A1 | Tumor Homing Statin Derivatives | Da Zen Theranostics, Inc. (US) | 2021-01-14 | — | — | US | disclosed |
| EP-3333155-A1 | METHOD FOR PRODUCING PITAVASTATIN CALCIUM | API Corporation (JP) | 2018-06-13 | — | — | EP | disclosed |
| EP-3299359-A1 | CRYSTALLINE AND AMORPHOUS FORMS OF PITAVASTATIN HEMICALCIUM SALT | Nissan Chemical Industries, Ltd. (JP) | 2018-03-28 | — | — | EP | disclosed |
| EP-2788341-B1 | PROCESS FOR THE PREPARATION OF A THIOPRECURSOR FOR STATINS | DSM SINOCHEM PHARM NL BV (NL) | 2017-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210008217-A1 | Tumor Homing Statin Derivatives | HMGCR, DHCR7, DHODH | RXRA 2237/4885PRKAA2 4128/4885NR1I2 1725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.