Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.64 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | HMGCR | P04035 | 2/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18696397 | 0.88 | RXRA (0.65) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL244423 | 0.87 | RXRA (0.67) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL28287583 | 0.87 | RXRA (0.64) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL29419163 | 0.87 | RXRA (0.67) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL526489 | 0.85 | RXRA (0.68) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL10129907 | 0.85 | RXRA (0.68) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL526488 | 0.85 | RXRA (0.68) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL29466456 | 0.83 | RXRA (0.75) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL1844436 | 0.83 | RXRA (0.75) | RXRAPRKAA2NR1I2NR4A2PDE4D | |
| SCHEMBL1843198 | 0.83 | RXRA (0.75) | RXRAPRKAA2NR1I2NR4A2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641762-B1 | Process for preparation of 5-hydroxy-3-ketoester derivative and optically active substance thereof | UBE INDUSTRIES (JP) | 1997-05-28 | — | — | EP | disclosed |
| US-5457225-A | Process for preparation of 5-hydroxy-3-ketoester derivative and optically active substance thereof | UBE INDUSTRIES LTD. (JP) | 1995-10-10 | — | — | US | disclosed |
| EP-0641762-A1 | Process for preparation of 5-hydroxy-3-ketoester derivative and optically active substance thereof | UBE INDUSTRIES, LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |