Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.32 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.32 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001848 | 1.00 | MAPT (0.36) | MAPTGAAPRKCAHTTSMN1; SMN2 | |
| SCHEMBL647676 | 1.00 | MAPT (0.36) | MAPTGAAPRKCAHTTSMN1; SMN2 | |
| SCHEMBL1828803 | 1.00 | MAPT (0.36) | MAPTGAAPRKCAHTTSMN1; SMN2 | |
| SCHEMBL2810597 | 0.98 | GAA (0.36) | MAPTGAAPRKCAHTTSMN1; SMN2 | |
| SCHEMBL2814073 | 0.93 | GAA (0.36) | MAPTGAAHTTSMN1; SMN2MEN1 | |
| SCHEMBL13009446 | 0.87 | GAA (0.39) | GAAMEN1KMT2A | |
| SCHEMBL4446863 | 0.85 | GAA (0.38) | GAAHTTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8838256 | 0.79 | ALDH1A1 (0.34) | MAPTGAAHTTMEN1KMT2A | |
| SCHEMBL9335192 | 0.79 | LTA4H (0.36) | MAPTGAAMEN1KMT2AMMP2 | |
| SCHEMBL677282 | 0.79 | LTA4H (0.36) | MAPTGAAMEN1KMT2AMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8471031-B2 | Process for the preparation of sterically hindered nitroxyl ethers | BASF SE (DE) | 2013-06-25 | — | — | US | disclosed |
| US-8471031-B2 | Process for the preparation of sterically hindered nitroxyl ethers | BASF SE (DE) | 2013-06-25 | — | — | US | disclosed |
| US-8471031-B2 | Process for the preparation of sterically hindered nitroxyl ethers | BASF SE (DE) | 2013-06-25 | — | — | US | disclosed |
| CN-101484422-B | Process for the preparation of sterically hindered nitroxyl ethers | CIBA HOLDING INC | 2012-07-11 | — | — | CN | disclosed |
| EP-2035381-B1 | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS | BASF SE (DE) | 2010-12-29 | — | — | EP | disclosed |
| US-20100249401-A1 | Process for the preparation of sterically hindered nitroxyl ethers | BASF SE (DE) | 2010-09-30 | — | — | US | disclosed |
| US-20100249401-A1 | Process for the preparation of sterically hindered nitroxyl ethers | BASF SE (DE) | 2010-09-30 | — | — | US | disclosed |
| US-20100249401-A1 | Process for the preparation of sterically hindered nitroxyl ethers | BASF SE (DE) | 2010-09-30 | — | — | US | disclosed |
| CN-101484422-A | Process for the preparation of sterically hindered nitroxyl ethers | CIBA HOLDING INC (CH) | 2009-07-15 | — | — | CN | disclosed |
| EP-2035381-A1 | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS | Ciba Holding Inc. (CH) | 2009-03-18 | — | — | EP | disclosed |
| WO-2008003602-A1 | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS | CIBA HOLDING INC. (CH) | 2008-01-10 | — | — | WO | disclosed |
| WO-2008003602-A1 | PROCESS FOR THE PREPARATION OF STERICALLY HINDERED NITROXYL ETHERS | CIBA HOLDING INC. (CH) | 2008-01-10 | — | — | WO | disclosed |
| US-20070191516-A1 | Process for the synthesis of amine ethers | CIBA SPECIALTY CHEMICALS CORP. | 2007-08-16 | — | — | US | disclosed |
| US-20070191516-A1 | Process for the synthesis of amine ethers | CIBA SPECIALTY CHEMICALS CORP. | 2007-08-16 | — | — | US | disclosed |
| US-20070191516-A1 | Process for the synthesis of amine ethers | CIBA SPECIALTY CHEMICALS CORP. | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191516-A1 | Process for the synthesis of amine ethers | AOC2, AOX1, AKR7A2 | MAPT 2680/4885GAA 3860/4885PRKCA 4880/4885 |
| US-20100249401-A1 | Process for the preparation of sterically hindered nitroxyl ethers | PPOX, CBR1, CBR3 | MAPT 1624/4885GAA 1862/4885PRKCA 4248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.