Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1863082 | 0.82 | KMT2A (0.56) | KMT2AMAPTMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL1858862 | 0.82 | KMT2A (0.56) | KMT2AMAPTMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL1870536 | 0.81 | MAPT (0.66) | KMT2AMAPTMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL1865941 | 0.80 | KMT2A (0.54) | KMT2AMAPTMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL31473390 | 0.80 | JAK2 (0.42) | KMT2AMAPTMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL12018989 | 0.79 | KMT2A (0.53) | KMT2AMAPTMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL12019948 | 0.79 | KDM1A (0.43) | KMT2AMAPTMEN1SMN1; SMN2RAB9A | |
| SCHEMBL1866824 | 0.76 | KMT2A (0.66) | KMT2AMAPTMEN1SMN1; SMN2MAPK1 | |
| SCHEMBL30989701 | 0.73 | VCAM1 (0.47) | KMT2AMAPTMEN1SMN1; SMN2RAB9A | |
| SCHEMBL1860221 | 0.73 | KDM1A (0.50) | KMT2AMAPTSMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493857-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | Ariel-University Research and Development Company Ltd. (IL) | 2012-09-05 | — | — | EP | claimed |
| US-20120220537-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2012-08-30 | — | — | US | claimed |
| WO-2011051950-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD (IL) | 2011-05-05 | — | — | WO | claimed |
| EP-2493857-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | Ariel-University Research and Development Company Ltd. (IL) | 2012-09-05 | — | — | EP | disclosed |
| US-20120220537-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD. (IL) | 2012-08-30 | — | — | US | disclosed |
| WO-2011051950-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD (IL) | 2011-05-05 | — | — | WO | disclosed |
| WO-2011051950-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | ARIEL-UNIVERSITY RESEARCH AND DEVELOPMENT COMPANY LTD (IL) | 2011-05-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220537-A1 | 9-AMINOACRIDINE DERIVATIVES, THEIR PREPARATION AND USES | MPG, PRMT9, AADAT | KMT2A 848/4885MAPT 4188/4885MEN1 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.