Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | ADK | P55263 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | WHR1 | P49842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24054474 | 0.83 | KMT2A (0.46) | ADORA2AADORA1ADORA3MEN1KMT2A | |
| SCHEMBL22097185 | 0.78 | MMP12 (0.32) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL19016950 | 0.77 | DPP4 (0.33) | DPP4ADORA2AADORA1ADORA3L3MBTL1 | |
| SCHEMBL21849792 | 0.72 | TDO2 (0.37) | HTR2AHTR2CHTR2BADORA2AADORA1 | |
| SCHEMBL24279824 | 0.69 | KDM4E (0.35) | MEN1KMT2AHSD17B10SMN1; SMN2POLB | |
| SCHEMBL25100852 | 0.68 | HTR2A (0.50) | HTR2AHTR2CHTR2BDPP4ADK | |
| SCHEMBL9821295 | 0.68 | LMNA (0.54) | HTR2AHTR2CHTR2BPOLBL3MBTL1 | |
| SCHEMBL29881705 | 0.68 | LMNA (0.54) | HTR2AHTR2CHTR2BPOLBL3MBTL1 | |
| SCHEMBL16824569 | 0.68 | TNKS (0.46) | MEN1KMT2AHSD17B10SMN1; SMN2POLB | |
| SCHEMBL21636291 | 0.66 | MEN1 (0.35) | ADORA2AADORA1ADORA3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150604-A1 | BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLYL GROUPS, CARBAZOLYL GROUPS, BENZOFURANE GROUPS OR BENZOTHIOPHENE GROUPS FOR ORGANIC LIGHT EMITTING DIODES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-04-05 | — | — | EP | disclosed |