SCHEMBL18698677

SCHEMBL18698677

Cc1ccccc1-c1ccccc1Sc1ccc(S(C)(=O)=O)cc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 15/20 0.45
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HKDC1 Q2TB90 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KDM4E B2RXH2 1/20 0.38
NSD2 O96028 1/20 0.38
MAPK1 P28482 1/20 0.38
PTGS1 P23219 3/20 0.37
DRD1 P21728 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14712815 0.83 PTGS2 (0.64) PTGS2PTGS1
SCHEMBL16638368 0.80 CA2 (0.42) CA12CA1CA2CA9MAPT
SCHEMBL19365898 0.80 MAPT (0.50) MAPTMEN1KMT2AHKDC1NPSR1
SCHEMBL12361695 0.79 MAPT (0.47) MAPTMEN1KMT2AHKDC1NPSR1
SCHEMBL15606260 0.77 NR1H2 (0.45) MAPTMEN1KMT2AHKDC1NPSR1
SCHEMBL3282090 0.75 TSHR (0.43) CA12CA1CA2CA9
SCHEMBL25430599 0.75 PTGS2 (0.50) PTGS2PTGS1DRD1
SCHEMBL28301092 0.74 PTGS2 (0.71) PTGS2CA12CA1CA2CA9
SCHEMBL15834156 0.74 TP53 (0.38) PTGS2MAPTMEN1KMT2AHKDC1
SCHEMBL17301737 0.74 HTR1A (0.46) MAPTMEN1KMT2AHKDC1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9612535-B2 Pattern forming method, electron beam- or extreme ultraviolet-sensitive resin composition, resist film using the same, method of manufacturing electronic device, and electronic device FUJIFILM CORPORATION (JP) 2017-04-04 US disclosed