Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18699136 | 0.86 | TP53 (0.38) | — | |
| SCHEMBL17813819 | 0.81 | ALDH1A1 (0.34) | ELANEHPGDSMN1; SMN2 | |
| SCHEMBL18699197 | 0.80 | ALDH1A1 (0.35) | — | |
| SCHEMBL17808288 | 0.77 | HMGCR (0.32) | ELANE | |
| SCHEMBL20091003 | 0.75 | IRAK4 (0.33) | — | |
| SCHEMBL16386821 | 0.73 | SLC13A5 (0.40) | HPGDSMN1; SMN2 | |
| SCHEMBL18751309 | 0.72 | GABRA1 (0.39) | HPGDSMN1; SMN2 | |
| SCHEMBL17040561 | 0.72 | GABRA1 (0.39) | HPGDSMN1; SMN2 | |
| SCHEMBL12796017 | 0.69 | CA1 (0.31) | — | |
| SCHEMBL13636034 | 0.69 | NOS3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611248-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2017-04-04 | — | — | US | disclosed |