Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 8/20 | 0.46 |
| ▸ | DRD2 | P14416 | 6/20 | 0.46 |
| ▸ | DRD3 | P35462 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18699453 | 0.84 | DRD4 (0.47) | DRD4DRD2DRD3MAPTNPSR1 | |
| SCHEMBL18699520 | 0.83 | DRD4 (0.46) | DRD4DRD2DRD3MAPTNPSR1 | |
| SCHEMBL18699539 | 0.82 | DRD4 (0.51) | DRD4DRD2DRD3MAPTNPSR1 | |
| SCHEMBL18699458 | 0.81 | HTR1A (0.44) | DRD4DRD2DRD3 | |
| SCHEMBL12000243 | 0.70 | DRD4 (0.64) | DRD4DRD2DRD3MAPTNPSR1 | |
| SCHEMBL18699541 | 0.70 | DRD2 (0.48) | DRD4DRD2DRD3MAPTNPSR1 | |
| SCHEMBL2597773 | 0.69 | DRD4 (0.72) | DRD4DRD2DRD3MAPTL3MBTL1 | |
| SCHEMBL418557 | 0.68 | DRD4 (0.57) | DRD4DRD2DRD3MAPTNPSR1 | |
| SCHEMBL14132945 | 0.67 | DRD4 (0.59) | DRD4DRD2DRD3MAPTNPSR1 | |
| SCHEMBL7426690 | 0.66 | DRD4 (0.68) | DRD4DRD2DRD3MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150591-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF BENZO[B]THIOPHENE COMPOUNDS | Crystal Pharma S.A.U (ES) | 2017-04-05 | — | — | EP | disclosed |