Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28843653 | 0.84 | MAPT (0.36) | ANPEPERAP2POLBMAPT | |
| SCHEMBL6049095 | 0.80 | MAPT (0.48) | ANPEPERAP2MEN1KMT2APOLB | |
| SCHEMBL3429276 | 0.80 | MEN1 (0.44) | ANPEPERAP2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3427720 | 0.77 | CXCR4 (0.43) | ANPEPERAP2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8007175 | 0.75 | TPI1 (0.32) | MAPT | |
| SCHEMBL685503 | 0.75 | PAOX (0.36) | POLB | |
| SCHEMBL3429763 | 0.74 | MEN1 (0.45) | ANPEPERAP2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14268088 | 0.72 | POLB (0.39) | MEN1KMT2ASMN1; SMN2POLBSIGMAR1 | |
| SCHEMBL28831058 | 0.72 | GNAI3 (0.34) | — | |
| SCHEMBL7453394 | 0.71 | MAPT (0.50) | ANPEPERAP2MEN1KMT2ACHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060338-A1 | CRYSTALLINE FORMS OF FOSNETUPITANT | HELSINN HEALTHCARE SA (CH) | 2017-04-13 | — | — | WO | disclosed |