Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3429276 | 0.89 | MEN1 (0.44) | CXCR4MEN1KMT2AANPEPERAP2 | |
| SCHEMBL3429763 | 0.86 | MEN1 (0.45) | CXCR4MEN1KMT2AANPEPERAP2 | |
| SCHEMBL21577443 | 0.82 | HRH2 (0.41) | CXCR4MEN1KMT2AANPEPERAP2 | |
| SCHEMBL3427283 | 0.80 | CSNK2A2 (0.41) | MEN1KMT2ACSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL3427278 | 0.80 | CSNK2A2 (0.41) | CSNK2A2CSNK2BCSNK2A1CSNK2A3LPAR3 | |
| SCHEMBL18705243 | 0.77 | ANPEP (0.39) | CXCR4MEN1KMT2AANPEPERAP2 | |
| SCHEMBL8735121 | 0.76 | GRIN2D (0.55) | CXCR4MEN1KMT2AANPEPERAP2 | |
| SCHEMBL584267 | 0.75 | MEN1 (0.51) | CXCR4MEN1KMT2AHRH2HRH1 | |
| SCHEMBL9749886 | 0.75 | GRIN2D (0.69) | MAPT | |
| SCHEMBL25226579 | 0.74 | GRIN2D (0.50) | CXCR4ANPEPERAP2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10849916-B2 | Stable liquid formulations of cyclophosphamide and its impurities | DR. REDDYS LABORATORIES LIMITED (IN) | 2020-12-01 | — | — | US | disclosed |
| US-20190350948-A1 | NOVEL IMPURITIES OF CYCLOPHOSPHAMIDE LIQUID FORMULATIONS | AVYXA HOLDINGS, LLC (PR) | 2019-11-21 | — | — | US | disclosed |
| US-7691867-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2010-04-06 | — | — | US | disclosed |
| EP-1613619-B1 | QUINAZOLINE DERIVATIVES FOR TREATMENT OF CANCER | ASTRAZENECA AB (SE) | 2008-03-26 | — | — | EP | disclosed |
| US-20060270692-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | US | disclosed |
| EP-1613619-A1 | QUINAZOLINE DERIVATIVES FOR TREATMENT OF CANCER | AstraZeneca AB (SE) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004094410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10849916-B2 | Stable liquid formulations of cyclophosphamide and its impurities | CXCR5, F5, BCL6 | CXCR4 11/4885MEN1 2566/4885KMT2A 2529/4885 |
| US-20190350948-A1 | NOVEL IMPURITIES OF CYCLOPHOSPHAMIDE LIQUID FORMULATIONS | CXCR5, CXCR6, BCL6 | CXCR4 7/4885MEN1 3207/4885KMT2A 2499/4885 |
| US-20060270692-A1 | Chemical compounds | CCNI, MKI67, TP53 | CXCR4 2915/4885MEN1 241/4885KMT2A 2028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.