SCHEMBL18705335

SCHEMBL18705335

O=C(O)CCCC(C(=O)O)(N1C(=O)CCC1=O)N1C(=O)CCC1=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
LMNA P02545 3/20 0.34
SLC22A6 Q4U2R8 1/20 0.34
TSHR P16473 2/20 0.33
KMT2A Q03164 2/20 0.33
NFKB1 P19838 1/20 0.33
PMP22 Q01453 1/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
PTGS1 P23219 4/20 0.33
PTGS2 P35354 4/20 0.33
SCD O00767 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HTT P42858 1/20 0.32
PTGER3 P43115 1/20 0.32
PTGER2 P43116 1/20 0.32
CAMK2A Q9UQM7 1/20 0.31
F13A1 P00488 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL557138 0.93 TSHR (0.40) LMNASLC22A6TSHRKMT2ANFKB1
SCHEMBL1943663 0.93 TSHR (0.40) LMNASLC22A6TSHRKMT2ANFKB1
SCHEMBL1062014 0.89 ALDH1A1 (0.33) CYP1A2KMT2AMEN1ALDH1A1THRB
Citric Acid SCHEMBL8916871 0.83 ALDH1A1 (0.40) LMNATSHRKMT2ANFKB1PMP22
SCHEMBL21986417 0.82 EPHX2 (0.42) MAPK1SMN1; SMN2LMNATSHRALDH1A1
SCHEMBL29790176 0.82 KMT2A (0.32) SMN1; SMN2LMNATSHRKMT2ANFKB1
SCHEMBL378264 0.79 SCD (0.38) SMN1; SMN2SLC22A6TSHRKMT2AMEN1
SCHEMBL3953068 0.79 PTGER3 (0.35) LMNASLC22A6TSHRKMT2ANFKB1
SCHEMBL8818958 0.79 FABP4 (0.32) CYP1A2MAPK1SMN1; SMN2KMT2AMEN1
SCHEMBL3719747 0.77 ALDH1A1 (0.34) TSHRKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2739636-B1 OLIGOSACCHARIDES AND OLIGOSACCHARIDE-PROTEIN CONJUGATES DERIVED FROM CLOSTRIDIUM DIFFICILE POLYSACCARIDE PS-I, METHODS OF SYNTHESIS AND USES THEREOF, IN PARTICULAR AS VACCINES AND DIAGNOSTIC TOOLS MAX PLANCK GESELLSCHAFT (DE) 2018-09-26 EP claimed
CN-120121612-A Method for detecting polysaccharide molecular size of multivalent bacterial vaccine 兰州生物制品研究所有限责任公司 2025-06-10 CN disclosed
US-20250032635-A1 LIGAND-POLAR DRUG CONJUGATES TRIPARTITE THERAPEUTICS INC. (TW) 2025-01-30 US disclosed
US-12187817-B2 Preparation of ceramide conjugates and derivatives of sphingolipid analogues KODE BIOTECH LIMITED (NZ) 2025-01-07 US disclosed
WO-2024028192-A1 USE OF CONJUGATES OF HUMAN SERUM ALBUMIN AND PHOSPHOCHOLINE FOR BLOCKING C-REACTIVE PROTEIN PENTRACOR GMBH (DE) 2024-02-08 WO disclosed
US-20230374076-A1 THE PREPARATION OF CERAMIDE CONJUGATES AND DERIVATIVES OF SPHINGOLIPID ANALOGUES KODE BIOTECH LIMITED (NZ) 2023-11-23 US disclosed
US-11760779-B2 Preparation of ceramide conjugates and derivatives of sphingolipid analogues KODE BIOTECH LIMITED (NZ) 2023-09-19 US disclosed
US-20210369850-A1 COMPOUNDS AND THERAPEUTIC USES THEREOF Centauri Therapeutics Limited (GB/GB) (GB) 2021-12-02 US disclosed
CN-113433122-A Method for detecting polysaccharide molecular size of bacterial vaccine 兰州生物制品研究所有限责任公司 2021-09-24 CN disclosed
US-20210214396-A1 THE PREPARATION OF CERAMIDE CONJUGATES AND DERIVATIVES OF SPHINGOLIPID ANALOGUES KODE BIOTECH LIMITED (NZ) 2021-07-15 US disclosed
US-10953100-B2 Compounds and therapeutic uses thereof CENTUARI THERAPEUTICS LIMITED (GB/GB) (GB) 2021-03-23 US disclosed
WO-2018220603-A1 THE PREPARATION OF CERAMIDE CONJUGATES AND DERIVATIVES OF SPHINGOLIPID ANALOGUES BOVIN NICOLAI VLADIMIROVICH (RU) 2018-12-06 WO disclosed
US-20180280521-A1 COMPOUNDS AND THERAPEUTIC USES THEREOF CENTUARI THERAPEUTICS LIMITED (GB/GB) (GB) 2018-10-04 US disclosed
WO-2017060729-A1 COMPOUNDS AND THERAPEUTIC USES THEREOF CENTAURI THERAPEUTICS LIMITED (GB) 2017-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230374076-A1 THE PREPARATION OF CERAMIDE CONJUGATES AND DERIVATIVES OF SPHINGOLIPID ANALOGUES SGMS1, SGMS2, CERT1 CYP1A2 4408/4885MAPK1 4360/4885SMN1; SMN2 294/4885
US-11760779-B2 Preparation of ceramide conjugates and derivatives of sphingolipid analogues SGMS1, SGMS2, CERT1 CYP1A2 4370/4885MAPK1 4286/4885SMN1; SMN2 326/4885
US-20210214396-A1 THE PREPARATION OF CERAMIDE CONJUGATES AND DERIVATIVES OF SPHINGOLIPID ANALOGUES SGMS1, SGMS2, CERT1 CYP1A2 4425/4885MAPK1 4289/4885SMN1; SMN2 274/4885
US-20210369850-A1 COMPOUNDS AND THERAPEUTIC USES THEREOF CD47, MYD88, NFATC1 CYP1A2 4082/4885MAPK1 2815/4885SMN1; SMN2 3620/4885
US-12187817-B2 Preparation of ceramide conjugates and derivatives of sphingolipid analogues SGMS1, SGMS2, CERT1 CYP1A2 4357/4885MAPK1 4299/4885SMN1; SMN2 327/4885
US-20250032635-A1 LIGAND-POLAR DRUG CONJUGATES CD274, SELPLG, PDCD1LG2 CYP1A2 592/4885MAPK1 2680/4885SMN1; SMN2 3302/4885
US-10953100-B2 Compounds and therapeutic uses thereof CD47, MYD88, NFATC1 CYP1A2 4082/4885MAPK1 2815/4885SMN1; SMN2 3620/4885
US-20180280521-A1 COMPOUNDS AND THERAPEUTIC USES THEREOF CD47, MYD88, NFATC1 CYP1A2 4082/4885MAPK1 2815/4885SMN1; SMN2 3620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.