Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.46 |
| ▸ | GIGYF2 | Q6Y7W6 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.42 |
| ▸ | NOXO1 | Q8NFA2 | 1/20 | 0.42 |
| ▸ | LY6K | Q17RY6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18705366 | 0.93 | CSNK2A2 (0.46) | FOLH1SORT1PKMCSNK2A2CSNK2B | |
| SCHEMBL18705369 | 0.91 | GIGYF2 (0.47) | FOLH1GIGYF2SORT1PKMCSNK2A2 | |
| SCHEMBL20519815 | 0.87 | FOLH1 (0.57) | FOLH1SORT1PKMCSNK2A2CSNK2B | |
| SCHEMBL18736482 | 0.85 | GIGYF2 (0.53) | FOLH1GIGYF2SORT1PKMEGFR | |
| SCHEMBL18705334 | 0.83 | F2 (0.48) | FOLH1GIGYF2SORT1PKMCSNK2A2 | |
| SCHEMBL20520127 | 0.83 | PRSS1 (0.58) | FOLH1SORT1PKMCSNK2A2CSNK2B | |
| SCHEMBL20519966 | 0.83 | PRSS1 (0.58) | FOLH1SORT1PKMCSNK2A2CSNK2B | |
| SCHEMBL20519904 | 0.79 | FOLH1 (0.59) | FOLH1SORT1PKMCSNK2A2CSNK2B | |
| SCHEMBL18705384 | 0.79 | PRSS1 (0.48) | FOLH1GIGYF2SORT1PKMCSNK2A2 | |
| SCHEMBL20520128 | 0.78 | PRSS1 (0.56) | FOLH1GIGYF2SORT1PKMCSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060729-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | CENTAURI THERAPEUTICS LIMITED (GB) | 2017-04-13 | — | — | WO | disclosed |