Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 12/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM6A | O15550 | 1/20 | 0.42 |
| ▸ | TET3 | O43151 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | KDM4B | O94953 | 1/20 | 0.42 |
| ▸ | KDM5C | P41229 | 1/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.42 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.42 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29248280 | 0.81 | ELANE (0.46) | ELANEKDM4EKDM6BKDM6ATET3 | |
| SCHEMBL2178657 | 0.81 | L3MBTL1 (0.51) | ELANEL3MBTL1FEN1 | |
| SCHEMBL3747599 | 0.78 | ELANE (0.43) | ELANEKDM4EKDM6BKDM6ATET3 | |
| SCHEMBL29248189 | 0.76 | ELANE (0.42) | ELANEKDM4EKDM6BKDM6ATET3 | |
| SCHEMBL5484723 | 0.74 | ELANE (0.42) | ELANEKDM4EKDM6BKDM6ATET3 | |
| SCHEMBL3092371 | 0.74 | ELANE (0.49) | ELANEKDM4D | |
| SCHEMBL1574400 | 0.73 | CTSB (0.44) | ELANE | |
| SCHEMBL20551427 | 0.73 | KDM5A (0.44) | ELANEKDM4EKDM4CL3MBTL1FEN1 | |
| SCHEMBL3158083 | 0.72 | KDM4E (0.47) | ELANEKDM4EL3MBTL1FEN1LDHA | |
| SCHEMBL31037735 | 0.67 | KDM4E (0.53) | ELANEKDM4EKDM4DSLC22A12FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060874-A1 | N-SULFONYLATED PYRAZOLO[3,4-B]PYRIDIN-6-CARBOXAMIDES AND METHOD OF USE | ABBVIE S.Á.R.L (LU) | 2017-04-13 | — | — | WO | disclosed |