Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1573961 | 0.82 | SMN1; SMN2 (0.39) | KMT2ACYP1A2CYP2C19MEN1ALDH1A1 | |
| SCHEMBL1573842 | 0.82 | ACHE (0.47) | KMT2ACYP1A2CYP2C19MEN1ALDH1A1 | |
| SCHEMBL13246570 | 0.76 | MGLL (0.65) | KMT2ACYP1A2CYP2C19ALDH1A1CYP2C9 | |
| SCHEMBL18705459 | 0.73 | ELANE (0.47) | ELANE | |
| SCHEMBL1573944 | 0.72 | RAB9A (0.42) | KMT2AALDH1A1NPSR1SMN1; SMN2ACHE | |
| SCHEMBL1573858 | 0.72 | MAPT (0.43) | KMT2AMEN1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL1573967 | 0.72 | ACHE (0.44) | ELANEKMT2ACYP1A2CYP2C19MEN1 | |
| SCHEMBL13246475 | 0.71 | MGLL (0.62) | KMT2AFAAHSMN1; SMN2ACHEMGLL | |
| SCHEMBL1574081 | 0.70 | ALDH1A1 (0.49) | CTSBELANEKMT2ACYP1A2CYP2C19 | |
| SCHEMBL1148803 | 0.69 | KMT2A (0.47) | CTSBKMT2ACYP1A2CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713779-B1 | INDAZOLE DERIVATIVES AS INHIBITORS OF HORMONE-SENSITIVE LIPASES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-04-13 | — | — | EP | disclosed |
| CN-1914180-A | Indazole derivatives as hormone sensitive lipase inhibitors | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-02-14 | — | — | CN | disclosed |