Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LAP3 | P28838 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | GRN | P28799 | 1/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741147 | 0.83 | SLC7A5 (0.53) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| Alanine SCHEMBL9439316 | 0.82 | ALDH1A1 (0.53) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| D-Alanine SCHEMBL3421250 | 0.82 | ALDH1A1 (0.53) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| Alanine SCHEMBL516189 | 0.82 | ALDH1A1 (0.53) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL93452 | 0.82 | ALDH1A1 (0.61) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL93451 | 0.82 | ALDH1A1 (0.61) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL93453 | 0.82 | ALDH1A1 (0.61) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL3402343 | 0.80 | ALDH1A1 (0.53) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL18766260 | 0.80 | ALDH1A1 (0.53) | ALDH1A1LAP3MEN1LMNAKMT2A | |
| SCHEMBL3010038 | 0.80 | ALDH1A1 (0.53) | ALDH1A1LAP3MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017062622-A1 | SUPRAMOLECULAR MODIFICATION OF PROTEINS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-04-13 | — | — | WO | disclosed |