Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LAP3 | P28838 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.40 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucine SCHEMBL3052691 | 0.89 | SLC7A5 (0.69) | SLC7A5SLC1A3SLC1A2ALDH1A1LAP3 | |
| Alanine SCHEMBL9439316 | 0.85 | ALDH1A1 (0.53) | SLC7A5SLC1A3SLC1A2ALDH1A1LAP3 | |
| Alanine SCHEMBL516189 | 0.85 | ALDH1A1 (0.53) | SLC7A5SLC1A3SLC1A2ALDH1A1LAP3 | |
| D-Alanine SCHEMBL3421250 | 0.85 | ALDH1A1 (0.53) | SLC7A5SLC1A3SLC1A2ALDH1A1LAP3 | |
| SCHEMBL93453 | 0.84 | ALDH1A1 (0.61) | SLC7A5ALDH1A1LAP3MEN1LMNA | |
| SCHEMBL93452 | 0.84 | ALDH1A1 (0.61) | SLC7A5ALDH1A1LAP3MEN1LMNA | |
| SCHEMBL93451 | 0.84 | ALDH1A1 (0.61) | SLC7A5ALDH1A1LAP3MEN1LMNA | |
| Norleucine SCHEMBL15544530 | 0.83 | SLC1A2 (0.50) | SLC7A5SLC1A3SLC1A2ALDH1A1SLC1A1 | |
| Isoleucine SCHEMBL18705524 | 0.83 | ALDH1A1 (0.44) | SLC7A5SLC1A3SLC1A2ALDH1A1LAP3 | |
| Ammonia Solution, Strong SCHEMBL4650725 | 0.82 | ALDH1A1 (0.59) | SLC7A5ALDH1A1LAP3MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5604092-A | CONTACTING SERUM SAMPLE WITH DETECTABLY LABELED MONOCLONAL ANTIBODY WHICH BINDS TO HIV GAG PROTEIN, REMOVING UNBOUND ANTIBODIES, DETECTING BINDING WHICH INDICATES PRESENCE OF HIV | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1997-02-18 | — | — | US | disclosed |
| US-5405785-A | Quantitative analysis, radioimmunoassay,; complexing cyclosporine with labeled antibody; immunosuppressants | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1995-04-11 | — | — | US | disclosed |