Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 5/20 | 0.49 |
| ▸ | CNR2 | P34972 | 10/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL88281 | 0.88 | TRPC6 (0.49) | TRPC6CNR2PDE4BPDE4APDE4C | |
| SCHEMBL71158 | 0.87 | TRPC6 (0.48) | TRPC6CNR2PDE4BPDE4APDE4C | |
| SCHEMBL3633786 | 0.87 | TRPC6 (0.54) | TRPC6CNR2PDE4BPDE4APDE4C | |
| SCHEMBL21045798 | 0.82 | TRPC6 (0.55) | TRPC6CNR2 | |
| Potassium Ion SCHEMBL15757775 | 0.81 | TRPC6 (0.44) | TRPC6CNR2PDE4BPDE4APDE4C | |
| SCHEMBL30439691 | 0.81 | TRPC6 (0.54) | TRPC6CNR2 | |
| SCHEMBL21045633 | 0.81 | TRPC6 (0.54) | TRPC6CNR2 | |
| SCHEMBL15757242 | 0.79 | PDE4B (0.41) | TRPC6PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL26445599 | 0.78 | CNR2 (0.53) | CNR2 | |
| SCHEMBL72985 | 0.78 | PDE4D (0.59) | CNR2PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611250-B2 | Process for preparing 4-(cyclopropylmethoxy)-N-(3,5-dichloro-1-oxido-4-pyridyl)-5-methoxypyridine-2-carboxamide | SANOFI (FR) | 2017-04-04 | — | — | US | disclosed |