Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.53 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30680327 | 0.78 | CNR2 (0.66) | CNR2MAP4K4KMOCNR1 | |
| SCHEMBL411450 | 0.78 | CNR2 (0.66) | CNR2MAP4K4KMOCNR1 | |
| SCHEMBL18708221 | 0.78 | TRPC6 (0.49) | CNR2 | |
| SCHEMBL20594053 | 0.74 | KMO (0.59) | CNR2MAP4K4KMOCNR1 | |
| SCHEMBL30680252 | 0.74 | KMO (0.59) | CNR2MAP4K4KMOCNR1 | |
| SCHEMBL26445628 | 0.73 | CNR2 (0.48) | CNR2KMOCNR1 | |
| SCHEMBL20594044 | 0.73 | CNR2 (0.67) | CNR2CNR1 | |
| SCHEMBL8048393 | 0.72 | FFAR4 (0.51) | EP300KDM1A | |
| SCHEMBL26095416 | 0.71 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL30390133 | 0.70 | CNR2 (0.61) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3642200-B1 | PYRIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2023-05-03 | — | — | EP | disclosed |