Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1876349 | 0.82 | PTGS1 (0.51) | TSHRKDM4ERAB9ANPC1MAPT | |
| SCHEMBL1868858 | 0.80 | KDM4E (0.57) | TSHRKDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL1871212 | 0.80 | BCL2L1 (0.45) | TSHRKDM4ERAB9ANPC1MAPT | |
| SCHEMBL1876442 | 0.78 | PTGS1 (0.53) | TSHRKDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL28992360 | 0.77 | CES2 (0.57) | TSHRKDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL1878184 | 0.74 | HSD17B10 (0.44) | TSHRKDM4ERAB9AALDH1A1NPC1 | |
| SCHEMBL1871359 | 0.73 | PTGS1 (0.48) | KDM4ERAB9AALDH1A1NPC1MAPT | |
| SCHEMBL1866847 | 0.73 | RAB9A (0.58) | KDM4ERAB9AALDH1A1NPC1KMT2A | |
| SCHEMBL1881282 | 0.72 | HSD17B10 (0.40) | TSHRKDM4ERAB9AALDH1A1NPC1 | |
| Hydrochloric Acid SCHEMBL11840978 | 0.67 | CES2 (0.52) | RAB9AALDH1A1NPC1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496574-A1 | IMIDAZOPYRIDINES AS A NOVEL SCAFFOLD FOR MULTI-TARGETED KINASE INHIBITION | Abbott Laboratories (US) | 2012-09-12 | — | — | EP | claimed |
| WO-2011053476-A1 | IMIDAZOPYRIDINES AS A NOVEL SCAFFOLD FOR MULTI-TARGETED KINASE INHIBITION | ABBOTT LABORATORIES (US) | 2011-05-05 | — | — | WO | claimed |