Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.51 |
| ▸ | FABP4 | P15090 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.49 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.49 |
| ▸ | ADCY1 | Q08828 | 4/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.47 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12871205 | 0.86 | STIM1 (0.64) | MYCNPC1RAB9AKMT2ASTIM1 | |
| SCHEMBL11579267 | 0.81 | NPC1 (0.66) | MYCNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL12798177 | 0.81 | NPC1 (0.60) | MYCNPC1RAB9AKMT2ASTIM1 | |
| SCHEMBL12171364 | 0.79 | NPC1 (0.73) | MYCNPC1RAB9AKMT2AADCY1 | |
| SCHEMBL4395868 | 0.78 | NPC1 (0.72) | MYCNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL18708511 | 0.77 | MYC (0.50) | MYCNPC1RAB9AKMT2AADCY1 | |
| SCHEMBL10483674 | 0.76 | MYC (0.67) | MYCNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL2242305 | 0.76 | PRKAB2 (0.50) | FABP4PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4685014 | 0.75 | ALDH1A1 (0.55) | FABP4NPC1RAB9APRKAB2PRKAG1 | |
| SCHEMBL12171784 | 0.75 | NPC1 (0.62) | MYCNPC1RAB9AKMT2AADCY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611230-B2 | 1,3,4-oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease | PTC THERAPEUTICS, INC. (US) | 2017-04-04 | — | — | US | disclosed |