Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 12/20 | 0.50 |
| ▸ | DRD2 | P14416 | 11/20 | 0.50 |
| ▸ | DRD3 | P35462 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15637880 | 0.79 | DRD4 (0.52) | DRD4DRD2DRD3KDM4E | |
| SCHEMBL19676449 | 0.79 | DRD4 (0.52) | DRD4DRD2DRD3GAA | |
| SCHEMBL11896615 | 0.71 | DRD4 (1.00) | DRD4DRD2DRD3GAA | |
| Hydrochloric Acid SCHEMBL8042280 | 0.69 | DRD2 (0.69) | DRD4DRD2DRD3KDM4EMITF | |
| Hydrochloric Acid SCHEMBL8055377 | 0.69 | DRD4 (0.96) | DRD4DRD2DRD3GAA | |
| SCHEMBL10476759 | 0.69 | DRD4 (0.95) | DRD4DRD2DRD3GAA | |
| SCHEMBL19676414 | 0.69 | GLS (0.41) | KMT2AMEN1 | |
| SCHEMBL19549135 | 0.68 | KDM5B (0.48) | KDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8054973 | 0.68 | DRD4 (0.91) | DRD4DRD2DRD3GAA | |
| SCHEMBL8938905 | 0.67 | DRD4 (0.91) | DRD4DRD2DRD3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150582-A1 | INHIBITORS OF HISTONE DEMETHYLASES | GILEAD SCIENCES, INC. (US) | 2017-04-05 | — | — | EP | disclosed |