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SCHEMBL1871114

SCHEMBL1871114

O=C(Oc1ccccc1)c1ccc(C2=NC(c3c(Br)cc(Br)cc3Br)(n3c(-c4c(Br)cc(Br)cc4Br)nc(-c4ccc(C(=O)Oc5ccccc5)cc4)c3-c3ccc(C(=O)Oc4ccccc4)cc3)N=C2c2ccc(C(=O)Oc3ccccc3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AKT1 P31749 4/20 0.33
▸ AKT2 P31751 4/20 0.33
▸ MAPT P10636 4/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ TP53 P04637 2/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ FABP4 P15090 2/20 0.32
▸ FABP5 Q01469 2/20 0.32
▸ MAOA P21397 1/20 0.32
▸ MAOB P27338 1/20 0.32
▸ TDP1 Q9NUW8 2/20 0.32
▸ PRSS1 P07477 1/20 0.32
▸ ACR P10323 1/20 0.32
▸ TMPRSS15 P98073 1/20 0.32
▸ ALDH1A1 P00352 2/20 0.31
▸ LMNA P02545 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1869448 0.87 AKT1 (0.36) AKT1AKT2MAPTKMT2ANPC1
SCHEMBL1060659 0.86 AKT1 (0.41) AKT1AKT2MAPTTP53NPC1
SCHEMBL1060924 0.85 MGAM (0.36) AKT1AKT2
SCHEMBL1869206 0.83 MGAM (0.35) AKT1AKT2MAPTSMN1; SMN2FABP4
SCHEMBL1871953 0.82 AKT1 (0.32) AKT1AKT2MAPTKMT2ATP53
SCHEMBL1865917 0.80 FABP4 (0.33) AKT1AKT2MAPTKMT2ATP53
SCHEMBL1865541 0.78 FABP4 (0.39) AKT1AKT2MAPTNPC1SMN1; SMN2
SCHEMBL1870295 0.75 FABP4 (0.35) AKT1AKT2MAPTKMT2ANPC1
SCHEMBL2788962 0.74 TP53 (0.33) AKT1AKT2MAPTKMT2ATP53
SCHEMBL1869270 0.73 MGAM (0.38) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010111406-A2 COMPOUNDS AND THERAPEUTIC USES THEREOF MYRIAD PHARMACEUTICALS, INC. (US) 2010-09-30 — — WO claimed
US-7935776-B2 having a carboxy group in its main chain and a acryloyl group in its side chain; Color filters AGI CORPORATION (TW) 2011-05-03 — — US disclosed
US-7785501-B2 Black resin composition for display device, and member for display device DAI NIPPON PRINTING CO., LTD. (JP) 2010-08-31 — — US disclosed
US-20080318018-A1 Black Resin Composition for Display Device, and Member for Display Device DAI NIPPON PRINTING CO., LTD. (JP) 2008-12-25 — — US disclosed
US-20080234403-A1 Radiation curable and developable polyurethane and radiation curable and developable photo resist composition containing the same AGI CORPORATION (TW) 2008-09-25 — — US disclosed
US-6368774-B1 MIXTURE CONTAINING ISOINDOLININE DYE JSR CORPORATION (JP) 2002-04-09 — — US disclosed
US-6348298-B1 COMPOSITION CONSISTING OF COLORANT CONTAINING PHTHALOCYANINE BLUE AND PHTHALOCYANINE GREEN OR PIGMENT GREEN 36, ALKALI-SOLUBLE RESIN, POLYFUNCTIONAL MONOMER, AND PHOTOPOLYMERIZATION INITIATOR JSR CORPORATION (JP) 2002-02-19 — — US disclosed
US-6140019-A Radiation sensitive composition JSR CORPORATION (JP) 2000-10-31 — — US disclosed
EP-1033626-A1 Radiation sensitive composition JSR Corporation (JP) 2000-09-06 — — EP disclosed
EP-1033625-A1 Radiation sensitive composition JSR Corporation (JP) 2000-09-06 — — EP disclosed
US-6013415-A Radiation sensitive composition JSR CORPORATION (JP) 2000-01-11 — — US disclosed
EP-0893737-A2 Radiation sensitive composition JSR Corporation (JP) 1999-01-27 — — EP disclosed
EP-0866367-A2 Radiation sensitive composition JSR Corporation (JP) 1998-09-23 — — EP disclosed