SCHEMBL187152

SCHEMBL187152

COC(C(=O)O)=C(OC)c1ccc(O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.53
CA2 P00918 5/20 0.53
CA12 O43570 4/20 0.53
CA7 P43166 4/20 0.53
CA9 Q16790 4/20 0.53
CA14 Q9ULX7 4/20 0.53
CPT1B Q92523 1/20 0.47
CA3 P07451 1/20 0.45
TYR P14679 1/20 0.45
DRD1 P21728 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA5A P35218 1/20 0.45
CA5B Q9Y2D0 1/20 0.45
MAPT P10636 2/20 0.41
LMNA P02545 2/20 0.41
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
HPGD P15428 2/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL457034 0.84 TSHR (0.54) CA1CA12CA9MAPTLMNA
SCHEMBL27876289 0.82 TSHR (0.52) CA1CA12CA9MAPTLMNA
SCHEMBL27892981 0.82 TSHR (0.52) MAPTLMNAHPGDALDH1A1KMT2A
SCHEMBL16213551 0.75 CES2 (0.52) CA1CA2CA12CA7CA9
SCHEMBL7675491 0.73 TSHR (0.50) MAPTLMNAHPGDALDH1A1KMT2A
Hydroquinone SCHEMBL28272109 0.71 CA12 (0.61) CA1CA2CA12CA7CA9
SCHEMBL7959384 0.71 TSHR (0.52) MAPTLMNAHPGDALDH1A1KMT2A
SCHEMBL29625356 0.71 TSHR (0.52) MAPTLMNAHPGDKMT2AGAA
SCHEMBL6206058 0.70 TSHR (0.47) MAPTHPGDPKMHTTALDH1A1
SCHEMBL6207375 0.70 TSHR (0.47) MAPTHPGDPKMHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8653326-B2 Targeted DNA insertion in plants BAYER CROPSCIENCE N.V. (BE) 2014-02-18 US claimed
US-20100003759-A1 TARGETED DNA INSERTION IN PLANTS BAYER BIOSCIENCE N.V. (BE) 2010-01-07 US claimed
US-7598365-B2 Targeted DNA insertion in plants BAYER BIOSCIENCE N.V. (BE) 2009-10-06 US claimed
EP-1689870-A2 IMPROVED TARGETED DNA INSERTION IN PLANTS Bayer BioScience N.V. (BE) 2006-08-16 EP claimed
WO-2005049842-A2 IMPROVED TARGETED DNA INSERTION IN PLANTS BAYER BIOSCIENCE N.V. (BE) 2005-06-02 WO claimed
US-10570402-B2 Agrobacterium strains for plant transformation TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) 2020-02-25 US disclosed
US-20190085345-A1 AGROBACTERIUM STRAINS FOR PLANT TRANSFORMATION TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) 2019-03-21 US disclosed
US-10167479-B2 Agrobacterium strains for plant transformation TEMASEK LIFE SCIENCES LABORATORY LIMITED (SG) 2019-01-01 US disclosed
CN-108159035-A The new application of cinnamic acid derivative 天津中医药大学 2018-06-15 CN disclosed
CN-107881210-A The method and apparatus for characterizing antibiotic resistance in microorganism 伊拉斯谟大学鹿特丹医药中心 2018-04-06 CN disclosed
EP-2507376-B1 IMPROVED MEDIA COMPOSITIONS, SELECTION METHODS AND AGROBACTERIUM STRAINS FOR TRANSFORMATION OF PLANTS TEMASEK LIFE SCIENCES LAB LTD (SG) 2016-09-07 EP disclosed
US-20160046983-A1 Method of Diagnosis of Infection by Mycobacteria and Reagents Therefor TYRIAN DIAGNOSTICS LIMITED (AU) 2016-02-18 US disclosed
EP-0782581-A4 CLONING OF AN INSULIN-DEPENDENT MEMBRANE AMINOPEPTIDASE FROM GLUT-4 VESICLES BAYER AG (US) 2000-05-31 EP disclosed
WO-2000026348-A2 MAMMALIAN SUBTILISIN/KEXIN ISOZYME SKI-1: A PROPROTEIN CONVERTASE WITH A UNIQUE CLEAVAGE SPECIFICITY INSTITUT DE RECHERCHES CLINIQUES DE MONTREAL (CA) 2000-05-11 WO disclosed
US-5972680-A AN AMINOPEPTIDASE WHICH IS INVOLVED IN INSULIN REGULATION. BAYER CORPORATION (US) 1999-10-26 US disclosed
US-5968764-A DETECTING MODULATORS OF GLUCOSE TRANSPORT PROTEIN; THERAPY FOR DIABETES AND DISORDERS OF INSULIN RESISTANCE, BY INCUBATING GLUCOSE TRANSPORT PROTEIN WITH TEST COMPOUND, ADDING TRANSPORT PROTEIN SUBSTRATE, MONITORING EFFECT BAYER CORPORATION (US) 1999-10-19 US disclosed
EP-0900279-A1 IMPROVED TRANSFORMATION METHOD FOR PLANTS PLANT GENETIC SYSTEMS N.V. (BE) 1999-03-10 EP disclosed
WO-1998037212-A1 IMPROVED TRANSFORMATION METHOD FOR PLANTS PLANT GENETIC SYSTEMS, N.V. (BE) 1998-08-27 WO disclosed
EP-0782581-A1 CLONING OF AN INSULIN-DEPENDENT MEMBRANE AMINOPEPTIDASE FROM GLUT-4 VESICLES Bayer Corporation (US) 1997-07-09 EP disclosed
WO-1996009317-A1 CLONING OF AN INSULIN-DEPENDENT MEMBRANE AMINOPEPTIDASE FROM GLUT-4 VESICLES BAYER CORPORATION (US) 1996-03-28 WO disclosed