SCHEMBL457034

SCHEMBL457034

COC(C(=O)O)=C(OC)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
SRC P12931 1/20 0.48
KMT2A Q03164 3/20 0.43
MAPT P10636 3/20 0.43
KDM4E B2RXH2 2/20 0.43
MEN1 O00255 2/20 0.43
ALDH1A1 P00352 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
GLA P06280 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CES1 P23141 5/20 0.42
CES2 O00748 3/20 0.42
HPGD P15428 2/20 0.42
GAA P10253 1/20 0.42
ALOX15 P16050 2/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27892981 0.98 TSHR (0.52) TSHRSRCKMT2AMAPTKDM4E
SCHEMBL27876289 0.98 TSHR (0.52) TSHRSRCKMT2AMAPTKDM4E
SCHEMBL7675491 0.88 TSHR (0.50) TSHRSRCKMT2AMAPTKDM4E
SCHEMBL7959384 0.86 TSHR (0.52) TSHRSRCKMT2AMAPTKDM4E
SCHEMBL29625356 0.86 TSHR (0.52) TSHRSRCKMT2AMAPTRAB9A
SCHEMBL6207375 0.85 TSHR (0.47) TSHRSRCKMT2AMAPTALDH1A1
SCHEMBL6206060 0.85 TSHR (0.47) TSHRKMT2AMAPTALDH1A1NPC1
SCHEMBL6206058 0.85 TSHR (0.47) TSHRSRCKMT2AMAPTALDH1A1
SCHEMBL187152 0.84 CA1 (0.53) KMT2AMAPTALDH1A1CES2HPGD
SCHEMBL6576791 0.81 TSHR (0.56) TSHRSRCKMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3307395-B1 SOLUBILISING AGENTS FOR UV SCREENING COMPOUNDS ISP INVESTMENTS LLC (US) 2020-08-05 EP claimed
EP-3600224-A1 SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP Investments LLC (US) 2020-02-05 EP claimed
CN-107366470-B Sisal fiber tent for field taking up quarters cloth 广西师范学院 2019-06-25 CN claimed
WO-2018175836-A1 SKIN CARE COMPOSITIONS COMPRISING A TERPOLYMER, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2018-09-27 WO claimed
CN-108181388-A A kind of method for differentiating willow type propolis and yang gum 中国农业科学院蜜蜂研究所 2018-06-19 CN claimed
EP-3310444-A1 WATER-IN-OIL SUNSCREEN COMPOSITION HAVING ORGANIC SUNSCREEN ACTIVES L'Oréal (FR) 2018-04-25 EP claimed
WO-2016204946-A1 WATER-IN-OIL SUNSCREEN COMPOSITION HAVING ORGANIC SUNSCREEN ACTIVES L'OREAL (FR) 2016-12-22 WO claimed
US-20160367470-A1 WATER-IN-OIL SUNSCREEN COMPOSITION HAVING ORGANIC SUNSCREEN ACTIVES L'OREAL (FR) 2016-12-22 US claimed
CN-102746344-A Cinnamic acid derivative crystal and preparation method thereof UNIV SHANDONG TECHNOLOGY 2012-10-24 CN claimed
CN-102746160-A Cinnamic acid derivative crystal and preparation method thereof UNIV SHANDONG TECHNOLOGY 2012-10-24 CN claimed
CN-102397324-A Method for determining phenylpropanoid glycosides in Tibetan medicine lamiophlomis rotata LANZHOU CHEM PHYS INST 2012-04-04 CN claimed
US-7534421-B2 s-Triazine compounds bearing at least one para-aminobenzalmalonic salt substituent and photoprotective cosmetic compositions comprised thereof L'OREAL (FR) 2009-05-19 US claimed
US-20080287294-A1 Method of Mollusc Control SYNGENTA CROP PROTECTION, INC. (US) 2008-11-20 US claimed
EP-1865771-A1 METHOD OF MOLLUSC CONTROL Syngeta Participations AG (CH) 2007-12-19 EP claimed
WO-2006108553-A1 METHOD OF MOLLUSC CONTROL SYNGENTA PARTICIPATIONS AG. (CH) 2006-10-19 WO claimed
US-6451334-B2 PULSE ADMINISTERING OF A C1-C4 SUBSTITUTED AND/OR PHENYL SUBSTITUTED CARBOXYLIC ACID AND SALTS AND A CARRIER OR DILUENT TO STIMULATE CELLS IN TREATING BLOOD DISORDERS, E.G. SICKLE CELL ANEMIA, THALASSEMIA, BLOOD LOSS ETC. Perrine, Susan P. 2002-09-17 US claimed
WO-2002015691-A1 USE FOR CONIFER SAPLING PROTECTION AGAINST INSECT ATTACK ROBIGUS AB (SE) 2002-02-28 WO claimed
EP-3040380-B1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE IDEMITSU KOSAN CO (JP) 2026-02-25 EP disclosed
US-5087671-A Insoluble polymers containing reactive groups THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) 1992-02-11 US disclosed
US-4910200-A Agricultural fungicide CELAMERCK GMBH & CO. KG (DE) 1990-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080287294-A1 Method of Mollusc Control TBCB, DDT, TUBB2B TSHR 633/4885SRC 4496/4885KMT2A 683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.