Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 5/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.33 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.32 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18062 | 0.95 | CCR5 (0.39) | CCR5SLC5A1SLC5A2HTR2CSLC6A4 | |
| SCHEMBL18178 | 0.87 | SLC5A2 (0.39) | CCR5SLC5A1SLC5A2SCN9A | |
| SCHEMBL17483 | 0.82 | SLC5A2 (0.40) | CCR5SLC5A1SLC5A2 | |
| SCHEMBL16238 | 0.77 | ACACB (0.36) | CCR5SLC5A1SLC5A2HTR2CSLC6A4 | |
| SCHEMBL16481264 | 0.75 | DRD1 (0.37) | LTA4H | |
| SCHEMBL17541 | 0.75 | SLC5A2 (0.59) | SLC5A1SLC5A2 | |
| SCHEMBL17916 | 0.74 | SLC5A2 (0.52) | CCR5SLC5A1SLC5A2 | |
| SCHEMBL25568 | 0.73 | SLC5A2 (0.40) | SLC5A1SLC5A2 | |
| SCHEMBL181059 | 0.71 | L3MBTL1 (0.45) | LTA4H | |
| SCHEMBL16239 | 0.70 | PARP15 (0.35) | CCR5SLC5A1SLC5A2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |