Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18171 | 0.76 | SLC5A2 (0.60) | SLC5A1SLC5A2 | |
| SCHEMBL17962 | 0.74 | SLC5A2 (0.39) | SLC5A1SLC5A2 | |
| SCHEMBL17916 | 0.73 | SLC5A2 (0.52) | CCR5SLC5A1SLC5A2 | |
| SCHEMBL18062 | 0.72 | CCR5 (0.39) | CCR5SLC5A1SLC5A2SCN9A | |
| SCHEMBL18722 | 0.70 | CCR5 (0.37) | CCR5SLC5A1SLC5A2SCN9A | |
| SCHEMBL16238 | 0.70 | ACACB (0.36) | CCR5SLC5A1SLC5A2SCN9A | |
| SCHEMBL181059 | 0.70 | L3MBTL1 (0.45) | — | |
| SCHEMBL181201 | 0.68 | CACNA1G (0.39) | CCR5SLC5A1SLC5A2 | |
| SCHEMBL27669068 | 0.67 | PYCR1 (0.37) | CCR5SLC5A1SLC5A2 | |
| SCHEMBL181117 | 0.67 | SLC5A2 (0.45) | CCR5SLC5A1SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025857-A1 | CYCLOALKYL METHOXYBENZYL PHENYL PYRAN DERIVATIVES AS SODIUM DEPENDENT GLUCOSE CO TRANSPORTER (SGLT2) INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2012-03-01 | — | — | WO | disclosed |