SCHEMBL187220

SCHEMBL187220

CN(CC1CO1)c1ccc(Cc2ccc(N(C)CC3CO3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CHRM2 P08172 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM3 P20309 1/20 0.36
MGLL Q99685 2/20 0.36
LMNA P02545 2/20 0.35
HDAC1 Q13547 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
POLB P06746 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
SLC5A1 P13866 1/20 0.30
SLC5A2 P31639 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12961267 0.93 ALDH1A1 (0.41) ALDH1A1CYP3A4TSHRMAPK1TDP1
SCHEMBL17354956 0.90 MEN1 (0.45) ALDH1A1CYP3A4TSHRTDP1MEN1
SCHEMBL18615654 0.87 ALDH1A1 (0.36) ALDH1A1CYP3A4TSHRMAPK1TDP1
SCHEMBL7157640 0.85 MEN1 (0.41) ALDH1A1MEN1KMT2ACHRM2LMNA
SCHEMBL17359261 0.83 MEN1 (0.41) ALDH1A1MEN1KMT2ALMNAPOLB
SCHEMBL1665729 0.83 MEN1 (0.55) ALDH1A1TSHRTDP1MEN1KMT2A
SCHEMBL9861061 0.82 MEN1 (0.38) TSHRMEN1KMT2ALMNA
SCHEMBL7776132 0.82 MEN1 (0.35) ALDH1A1MEN1KMT2ALMNAL3MBTL1
SCHEMBL10749521 0.81 MEN1 (0.40) ALDH1A1MEN1KMT2ALMNA
SCHEMBL15195722 0.81 ALDH1A1 (0.40) ALDH1A1CYP3A4TSHRMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 776 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023071921-A1 POLYAMIDE COMPOSITE MATERIAL, AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海金发科技发展有限公司 2023-05-04 WO claimed
CN-113999522-A Polyamide composite material and preparation method and application thereof 上海金发科技发展有限公司 2022-02-01 CN claimed
US-20210284881-A1 Fast Curing Epoxy Acrylic Liquid Shim Henkel IP & Holding GmbH (DE) 2021-09-16 US claimed
CN-111944309-A Polyamide composition capable of being stably molded 江苏金发科技新材料有限公司 2020-11-17 CN claimed
US-20140264822-A1 THERMOSETTING RESIN COMPOSITIONS WITH LOW COEFFICIENT OF THERMAL EXPANSION HENKEL CORPORATION (US) 2014-09-18 US claimed
US-8829694-B1 Thermosetting resin compositions with low coefficient of thermal expansion Henkel IP & Holding GmbH (DE) 2014-09-09 US claimed
US-20100285309-A1 PRIMER COMPOSITIONS FOR ADHESIVE BONDING SYSTEMS AND COATINGS HENKEL AG & CO. KGAA (DE) 2010-11-11 US claimed
US-20100151253-A1 Primer Compositions for Adhesive Bonding Systems HENKEL KGAA (DE) 2010-06-17 US claimed
EP-2190900-A2 PRIMER COMPOSITIONS FOR ADHESIVE BONDING SYSTEMS AND COATINGS Henkel AG & Co. KGaA (DE) 2010-06-02 EP claimed
WO-2009037323-A2 PRIMER COMPOSITIONS FOR ADHESIVE BONDING SYSTEMS AND COATINGS HENKEL AG & CO. KGAA (DE) 2009-03-26 WO claimed
US-20030131937-A1 Thermosetting resin compositions useful as underfill sealants HENKEL LOCTITE CORPORATION 2003-07-17 US claimed
US-20020117259-A1 Two part, room temperature curable epoxy resin/ (meth) acrylate compositions with high flash point and low odor, reaction products of which demonstrate improved fixture Henkel IP & Holding GmbH (DE) 2002-08-29 US claimed
US-20020058778-A1 Toughened thermosetting resin compositions useful as underfill sealants LOCTITE CORPORATION 2002-05-16 US claimed
US-20020058756-A1 Underfill sealants with improved adhesion, improved resistance to moisture absorption and improved resistance to stress cracking LOCTITE CORPORATION 2002-05-16 US claimed
US-6342577-B1 Thermosetting resin compositions useful as underfill sealants LOCTITE CORPORATION 2002-01-29 US claimed
US-6248204-B1 STRUCTURAL REINFORCEMENT COMPONENT THAT INCLUDES A HYDROPHOBIC FUMED SILICA IN AN AMOUNT OF ABOUT 5 TO ABOUT 20 WEIGHT PERCENT, BASED ON THE EPOXY RESIN COMPONENT LOCTITE CORPORATION 2001-06-19 US claimed
EP-0239804-B1 EPOXY RESINS BASED ON TETRAGLYCIDYL DIAMINES AND THE USE THEREOF FOR EPOXY SYSTEMS AND PREPREGS AMOCO CORPORATION (US) 1989-08-09 EP claimed
US-4814414-A POLYAMINE CURING AGENT, FIBER REINFORCEMENT, CO-POLYEPOXIDES; AIRCRAFT PREPREGS AMOCO CORPORATION (US) 1989-03-21 US claimed
EP-0239804-A1 Epoxy resins based on tetraglycidyl diamines and the use thereof for epoxy systems and prepregs AMOCO CORPORATION (US) 1987-10-07 EP claimed
US-4680341-A Epoxy resins based on tetraglycidyl diamines UNION CARBIDE CORPORATION (US) 1987-07-14 US claimed