Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9446083 | 0.89 | ACACB (0.39) | TSHRACACBACACA | |
| SCHEMBL1658197 | 0.83 | FDPS (0.34) | TSHR | |
| SCHEMBL8896558 | 0.83 | ACACB (0.35) | TSHRACACBACACA | |
| SCHEMBL14472608 | 0.82 | TSHR (0.39) | TSHRACACBACACA | |
| SCHEMBL19861383 | 0.80 | ACACB (0.36) | TSHRACACBACACA | |
| SCHEMBL20076356 | 0.80 | ACACB (0.36) | TSHRACACBACACA | |
| SCHEMBL8898822 | 0.80 | ACACB (0.36) | TSHRACACBACACA | |
| SCHEMBL8896548 | 0.79 | GPR84 (0.42) | ACACBACACA | |
| SCHEMBL8898934 | 0.79 | GGPS1 (0.41) | — | |
| SCHEMBL1658457 | 0.78 | TSHR (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617291-B2 | Tetradentate and octahedral metal complexes containing naphthyridinocarbazole and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2017-04-11 | — | — | US | disclosed |