Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19861383 | 1.00 | ACACB (0.36) | ACACBACACATSHR | |
| SCHEMBL8898822 | 1.00 | ACACB (0.36) | ACACBACACATSHR | |
| SCHEMBL8899208 | 0.94 | ACACB (0.46) | ACACBACACATSHR | |
| SCHEMBL9446083 | 0.90 | ACACB (0.39) | ACACBACACATSHR | |
| SCHEMBL1291170 | 0.88 | TSHR (0.36) | TSHR | |
| SCHEMBL8896558 | 0.84 | ACACB (0.35) | ACACBACACATSHR | |
| SCHEMBL8895374 | 0.80 | FFAR1 (0.50) | ACACBACACA | |
| SCHEMBL13106385 | 0.80 | ACACB (0.37) | ACACBACACA | |
| SCHEMBL18722151 | 0.80 | TSHR (0.36) | ACACBACACATSHR | |
| SCHEMBL8896548 | 0.80 | GPR84 (0.42) | ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647747-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2020-05-12 | — | — | US | disclosed |
| US-20180105558-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. | 2018-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647747-B2 | Cyclosporin derivatives and uses thereof | FKBP5, FKBP1B, MALT1 | ACACB 1776/4885ACACA 2171/4885TSHR 4095/4885 |
| US-20180105558-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | FKBP1B, MALT1, FKBP5 | ACACB 1771/4885ACACA 2462/4885TSHR 4131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.