Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 18/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 14/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14850538 | 0.77 | MTOR (0.40) | MTORPIK3CAADKNOS3NOS2 | |
| SCHEMBL19775310 | 0.75 | MTOR (0.44) | MTORPIK3CAADKNOS3NOS2 | |
| SCHEMBL10162703 | 0.74 | NOS3 (0.46) | MTORPIK3CAADKNOS3NOS2 | |
| SCHEMBL22666661 | 0.73 | APP (0.36) | — | |
| SCHEMBL23627445 | 0.71 | NOS3 (0.30) | NOS3NOS2 | |
| SCHEMBL503292 | 0.71 | MTOR (0.44) | MTORPIK3CAADKNOS3NOS2 | |
| SCHEMBL29571687 | 0.71 | MTOR (0.44) | MTORPIK3CAADKNOS3NOS2 | |
| SCHEMBL22066489 | 0.70 | ACACB (0.47) | — | |
| SCHEMBL10131245 | 0.69 | MTOR (0.43) | MTORPIK3CAADKNOS3NOS2 | |
| SCHEMBL6179282 | 0.69 | ALDH1A1 (0.47) | MTORPIK3CAADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617222-B1 | Alkynyl indazole derivative and use thereof | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2017-04-11 | — | — | US | disclosed |