Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18714259 | 0.74 | DRD2 (0.34) | — | |
| SCHEMBL22911966 | 0.74 | — | — | |
| SCHEMBL24078827 | 0.72 | SIRT6 (0.36) | — | |
| SCHEMBL18722778 | 0.71 | MTOR (0.40) | NOS3NOS2 | |
| SCHEMBL23627444 | 0.69 | NOS3 (0.31) | NOS3NOS1NOS2 | |
| SCHEMBL29317272 | 0.68 | NOS3 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL29578164 | 0.67 | — | — | |
| SCHEMBL2031652 | 0.67 | — | — | |
| SCHEMBL26178491 | 0.67 | — | — | |
| SCHEMBL20935616 | 0.67 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136464-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2021-07-08 | — | — | WO | disclosed |