Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 3/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18718217 | 0.82 | TUBB1 (0.49) | TUBB1PKMKMT2AMEN1FGFR2 | |
| SCHEMBL18733843 | 0.80 | TUBB1 (0.50) | TUBB1PKMKMT2AMEN1TNFRSF1A | |
| SCHEMBL18734054 | 0.79 | FGFR2 (0.35) | TUBB1FGFR2FGFR1 | |
| SCHEMBL18733594 | 0.78 | ALDH1A1 (0.51) | TUBB1PKMKMT2AMEN1KDM4E | |
| SCHEMBL17016803 | 0.76 | TUBB1 (0.43) | TUBB1PKMKMT2AMEN1APP | |
| SCHEMBL12907042 | 0.73 | TUBB1 (0.46) | TUBB1PKMKMT2AMEN1TNFRSF1A | |
| SCHEMBL16855852 | 0.72 | L3MBTL1 (0.42) | TUBB1KMT2AMEN1FGFR2KDM4E | |
| SCHEMBL16855936 | 0.71 | NQO1 (0.42) | FGFR2KDM4EMAPT | |
| SCHEMBL18718210 | 0.70 | TSHR (0.44) | KMT2AMEN1FGFR2MAPTRAB9A | |
| SCHEMBL16855940 | 0.70 | L3MBTL1 (0.42) | KMT2AMEN1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170101582-A1 | COMPOUND HAVING TETRAHYDROPYRAN RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2017-04-13 | — | — | US | disclosed |