Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18718217 | 0.86 | TUBB1 (0.49) | TUBB1PKMMAPTKMT2AMEN1 | |
| SCHEMBL18733594 | 0.82 | ALDH1A1 (0.51) | TUBB1PKMMAPTKMT2AMEN1 | |
| SCHEMBL9979113 | 0.80 | TUBB1 (0.36) | TUBB1MAPTFGFR2KDM4EGAA | |
| SCHEMBL9979114 | 0.80 | TUBB1 (0.36) | TUBB1MAPTFGFR2KDM4EGAA | |
| SCHEMBL17016803 | 0.80 | TUBB1 (0.43) | TUBB1PKMABL1ABCB1BCR | |
| SCHEMBL18733840 | 0.80 | TUBB1 (0.43) | TUBB1PKMABL1ABCB1BCR | |
| SCHEMBL12907042 | 0.77 | TUBB1 (0.46) | TUBB1PKMTNFRSF1AMAPTKMT2A | |
| SCHEMBL18734055 | 0.76 | FGFR2 (0.38) | TUBB1TNFRSF1AMAPTKMT2AMEN1 | |
| SCHEMBL16855928 | 0.76 | PRKCZ (0.44) | TUBB1MAPTKDM4EALDH1A1 | |
| SCHEMBL16855852 | 0.75 | L3MBTL1 (0.42) | TUBB1MAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9909064-B2 | Compound having tetrahydropyran ring, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2018-03-06 | — | — | US | disclosed |
| US-20170101582-A1 | COMPOUND HAVING TETRAHYDROPYRAN RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2017-04-13 | — | — | US | disclosed |