Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 6/20 | 0.63 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.63 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.47 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.47 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRND | Q07001 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28206145 | 0.91 | GRIA1 (0.64) | LNPEPERAP2GRIA1CA2CA1 | |
| SCHEMBL9716710 | 0.85 | ERAP2 (0.55) | LNPEPERAP2CA2CA1ITGB3 | |
| SCHEMBL7034236 | 0.85 | LNPEP (0.60) | LNPEPERAP2CA2CA1ITGB3 | |
| SCHEMBL9716715 | 0.85 | ERAP2 (0.55) | LNPEPERAP2CA2CA1ITGB3 | |
| SCHEMBL7034241 | 0.85 | LNPEP (0.60) | LNPEPERAP2CA2CA1ITGB3 | |
| SCHEMBL11278740 | 0.84 | CA2 (0.72) | LNPEPCA2CA1MMECTSL | |
| SCHEMBL11269522 | 0.84 | CA2 (0.72) | LNPEPCA2CA1MMECTSL | |
| Lysyl-Tyrosyl-Lysine Acetate SCHEMBL6275111 | 0.83 | NPY4R (0.62) | LNPEPERAP2ENPEPCHRNA1CHRNG | |
| SCHEMBL9318080 | 0.83 | SLC15A2 (0.60) | LNPEPERAP2GRIA1ENPEPCHRNA1 | |
| SCHEMBL9318061 | 0.83 | SLC15A2 (0.60) | LNPEPERAP2GRIA1ENPEPCHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170101459-A1 | CLEAVAGE AND EXCHANGE OF MAJOR HISTOCOMPATIBILITY COMPLEX LIGANDS EMPLOYING AZOBENZENE-CONTAINING PEPTIDES | STICHTING SANQUIN BLOEDVOORZIENING (NL) | 2017-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170101459-A1 | CLEAVAGE AND EXCHANGE OF MAJOR HISTOCOMPATIBILITY COMPLEX LIGANDS EMPLOYING AZOBENZENE-CONTAINING PEPTIDES | CD74, HLA-B, MICA | LNPEP 107/4885ERAP2 570/4885GRIA1 3646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.