Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.35 |
| ▸ | GNPAT | O15228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17164972 | 0.88 | NOD1 (0.45) | NOD1EPHX2CYP2C9MEN1KMT2A | |
| SCHEMBL17164973 | 0.88 | NOD1 (0.45) | NOD1EPHX2CYP2C9MEN1KMT2A | |
| SCHEMBL17164985 | 0.87 | GNPAT (0.43) | NOD1CA2CA4EPHX2FOLH1 | |
| SCHEMBL17164986 | 0.87 | GNPAT (0.43) | NOD1CA2CA4EPHX2FOLH1 | |
| SCHEMBL18735107 | 0.87 | MAPT (0.44) | NOD1CYP2C9PIN1FOLH1GNPAT | |
| SCHEMBL18735203 | 0.85 | ITGB1 (0.35) | CYP2C9 | |
| SCHEMBL18735396 | 0.83 | SMN1; SMN2 (0.33) | EPHX2CYP2C9MEN1KMT2A | |
| SCHEMBL18735395 | 0.83 | SMN1; SMN2 (0.33) | EPHX2CYP2C9MEN1KMT2A | |
| SCHEMBL17164991 | 0.80 | GNPAT (0.50) | NOD1EPHX2FOLH1RIMKLANAALAD2 | |
| SCHEMBL17164992 | 0.80 | GNPAT (0.50) | NOD1EPHX2FOLH1RIMKLANAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060400-A1 | PROTECTED CARBOXYLIC ACID-BASED METABOLITES FOR THE TREATMENT OF DISESASES RELATED TO MITOCHONDRIAL DYSFUNCTIONS | NEUROVIVE PHARMACEUTICAL AB (SE) | 2017-04-13 | — | — | WO | disclosed |