Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.38 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.38 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.38 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.38 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.38 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18734973 | 0.87 | NOD1 (0.41) | NOD1GNPATFOLH1CYP2C9PIN1 | |
| SCHEMBL17164972 | 0.85 | NOD1 (0.45) | NOD1GNPATFOLH1CYP2C9PIN1 | |
| SCHEMBL17164973 | 0.85 | NOD1 (0.45) | NOD1GNPATFOLH1CYP2C9PIN1 | |
| SCHEMBL17164985 | 0.81 | GNPAT (0.43) | NOD1GNPATFOLH1 | |
| SCHEMBL17164986 | 0.81 | GNPAT (0.43) | NOD1GNPATFOLH1 | |
| SCHEMBL18720196 | 0.77 | ITGB1 (0.41) | NOD1FOLH1 | |
| Dacisteine SCHEMBL2402188 | 0.77 | MAPT (0.55) | MAPTKDM4ETHRBALOX15NFKB1 | |
| Dacisteine SCHEMBL1814125 | 0.77 | MAPT (0.55) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL4907662 | 0.77 | ITGB1 (0.45) | MAPTKDM4ETHRBALOX15NFKB1 | |
| SCHEMBL4955697 | 0.77 | NOD1 (0.42) | ALDH1A1NOD1FOLH1CYP2C9PIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060400-A1 | PROTECTED CARBOXYLIC ACID-BASED METABOLITES FOR THE TREATMENT OF DISESASES RELATED TO MITOCHONDRIAL DYSFUNCTIONS | NEUROVIVE PHARMACEUTICAL AB (SE) | 2017-04-13 | — | — | WO | disclosed |