Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18735395 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2CYP2C9ALDH1A1ALDH2EPHX2 | |
| SCHEMBL18735399 | 0.92 | CYP2C9 (0.34) | SMN1; SMN2CYP2C9MEN1KMT2A | |
| SCHEMBL18735109 | 0.92 | CYP2C9 (0.34) | SMN1; SMN2CYP2C9MEN1KMT2A | |
| SCHEMBL17164978 | 0.88 | CYP2C9 (0.33) | SMN1; SMN2CYP2C9MEN1KMT2A | |
| SCHEMBL18735186 | 0.86 | CYP2C9 (0.30) | CYP2C9 | |
| SCHEMBL18735142 | 0.83 | KMT2A (0.39) | CYP2C9KMT2A | |
| SCHEMBL18734934 | 0.83 | — | — | |
| SCHEMBL18734973 | 0.83 | NOD1 (0.41) | CYP2C9EPHX2MEN1KMT2A | |
| SCHEMBL18735180 | 0.82 | ALOX15 (0.32) | — | |
| SCHEMBL18734935 | 0.81 | KMT2A (0.32) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060400-A1 | PROTECTED CARBOXYLIC ACID-BASED METABOLITES FOR THE TREATMENT OF DISESASES RELATED TO MITOCHONDRIAL DYSFUNCTIONS | NEUROVIVE PHARMACEUTICAL AB (SE) | 2017-04-13 | — | — | WO | disclosed |