Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 17/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18738075 | 0.89 | SIRT2 (0.45) | KIF11DNMT1SIRT2 | |
| SCHEMBL2546539 | 0.84 | KIF11 (0.54) | KIF11DNMT1 | |
| SCHEMBL29400681 | 0.84 | KIF11 (0.54) | KIF11DNMT1 | |
| SCHEMBL5967574 | 0.84 | KIF11 (0.54) | KIF11DNMT1 | |
| SCHEMBL14537462 | 0.81 | KIF11 (0.51) | KIF11DNMT1 | |
| SCHEMBL2403423 | 0.81 | KIF11 (0.48) | KIF11DNMT1 | |
| SCHEMBL2403426 | 0.81 | KIF11 (0.48) | KIF11DNMT1 | |
| SCHEMBL18736930 | 0.81 | KIF11 (0.48) | KIF11DNMT1SIRT2 | |
| SCHEMBL2466079 | 0.77 | PAM (0.46) | KIF11DNMT1 | |
| SCHEMBL2672737 | 0.77 | KIF11 (0.50) | KIF11DNMT1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017060420-A1 | PROTECTED FUMARIC ACID-BASED METABOLITES FOR THE TREATMENT OF AUTOIMMUNE DISEASES | NEUROVIVE PHARMACEUTICAL AB (SE) | 2017-04-13 | — | — | WO | disclosed |
| WO-2017060400-A1 | PROTECTED CARBOXYLIC ACID-BASED METABOLITES FOR THE TREATMENT OF DISESASES RELATED TO MITOCHONDRIAL DYSFUNCTIONS | NEUROVIVE PHARMACEUTICAL AB (SE) | 2017-04-13 | — | — | WO | disclosed |