Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 18/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2546539 | 0.88 | KIF11 (0.54) | KIF11DNMT1 | |
| SCHEMBL29400681 | 0.88 | KIF11 (0.54) | KIF11DNMT1 | |
| SCHEMBL5967574 | 0.88 | KIF11 (0.54) | KIF11DNMT1 | |
| SCHEMBL14537462 | 0.86 | KIF11 (0.51) | KIF11DNMT1 | |
| SCHEMBL2403426 | 0.86 | KIF11 (0.48) | KIF11DNMT1 | |
| SCHEMBL18736930 | 0.82 | KIF11 (0.48) | KIF11DNMT1 | |
| SCHEMBL18734982 | 0.81 | KIF11 (0.44) | KIF11DNMT1 | |
| SCHEMBL2672737 | 0.81 | KIF11 (0.50) | KIF11DNMT1 | |
| SCHEMBL2466079 | 0.81 | PAM (0.46) | KIF11DNMT1 | |
| SCHEMBL24359936 | 0.80 | KIF11 (0.46) | KIF11DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545033-A2 | PROPIONIC ACIDS, PROPIONIC ACID ESTERS, AND RELATED COMPOUNDS | Promentis Pharmaceuticals, Inc. (US) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011112535-A2 | PROPIONIC ACIDS, PROPIONIC ACID ESTERS, AND RELATED COMPOUNDS | PROMENTIS PHARMACEUTICALS, INC. (US) | 2011-09-15 | — | — | WO | disclosed |